Abstract
The aim of the study was to estimate the prevalence of familial history of type 2 diabetes among Arab diabetic patients, compare the maternal and paternal transmission of type 2 DM in patients and evaluate its influence on the clinical characteristics of this disease. This was a cross sectional study. The survey was carried out in urban and semi-urban primary health care [PHC] centers. Of the 2,400 registered with diagnosed diabetes, 1,980 agreed and gave their consent to take part in this study, thus giving a response rate of 82.5 %. DM was defined according to the WHO expert group. Of the study population, 72.9 % reported family history of DM. Family history of DM was significantly higher in females (54.2 %; p00.04) and in the age group below 30 years (24 %; p<0.001). The prevalence of diabetes was higher among patients with diabetic mother (25.4 % vs 22.1 %) and maternal aunts/uncles (31.2 % vs 22.2 %) compared to patients with diabetic father and paternal aunts/uncles. Family history of DM was higher in patients of consanguineous parents (77.4 %) than those of nonconsanguineous parents (70.4 %). The present study has found a significant maternal effect in transmission of T2 DM. Family history is associated with the increased incidence of diabetes.
| Original language | English |
|---|---|
| Pages (from-to) | 90-92 |
| Number of pages | 3 |
| Journal | International Journal of Diabetes in Developing Countries |
| Volume | 32 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Jun 2012 |
| Externally published | Yes |
Keywords
- Diabetes mellitus
- Family history
- Genetic disorders
- Parental transmission
