TY - JOUR
T1 - Fertility preservation is an imperative goal in the clinical practice of radiation oncology
T2 - a narrative review
AU - Ahmed, Yumna
AU - Khan, Agha Muhammad Hammad
AU - Rao, Urooba Jawwad
AU - Shaukat, Fatima
AU - Jamil, Arhum
AU - Hasan, Syed Mohammad
AU - Abrar, Sehrish
AU - Qureshi, Bilal Mazhar
AU - Abbasi, Ahmed Nadeem
N1 - Publisher Copyright:
© the authors; licensee ecancermedicalscience. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
PY - 2022
Y1 - 2022
N2 - With reduced cancer mortality in recent years, increased efforts must be put into safeguarding cancer survivors' long-term quality of life (QOL). Fertility preservation is recognised as a key component of QOL in survivorship. Concerns about fertility have been seen to significantly impact cancer patients' emotional and mental health as, generally, both malignancy and its treatment may cause a temporary or permanent reduction in infertility. This article reviews the primary effects of radiation therapy on male and female gonads and has further highlighted procedures through which the functioning of these organs can be protected before or during radiation treatment. We have also emphasised the importance of the establishment of multidisciplinary tumour boards and patient education regarding future reproductive function which is an important component of the care of individuals with cancer. This article highlights that infertility is a persistent and major concern that can add to long-term stress in cancer survivors, and education about fertility preservation before the initiation of any treatment is especially important.
AB - With reduced cancer mortality in recent years, increased efforts must be put into safeguarding cancer survivors' long-term quality of life (QOL). Fertility preservation is recognised as a key component of QOL in survivorship. Concerns about fertility have been seen to significantly impact cancer patients' emotional and mental health as, generally, both malignancy and its treatment may cause a temporary or permanent reduction in infertility. This article reviews the primary effects of radiation therapy on male and female gonads and has further highlighted procedures through which the functioning of these organs can be protected before or during radiation treatment. We have also emphasised the importance of the establishment of multidisciplinary tumour boards and patient education regarding future reproductive function which is an important component of the care of individuals with cancer. This article highlights that infertility is a persistent and major concern that can add to long-term stress in cancer survivors, and education about fertility preservation before the initiation of any treatment is especially important.
KW - cryopreservation
KW - oncofertility
KW - ovarian transposition
KW - radiation
KW - tumour board
UR - http://www.scopus.com/inward/record.url?scp=85147829225&partnerID=8YFLogxK
U2 - 10.3332/ecancer.2022.1461
DO - 10.3332/ecancer.2022.1461
M3 - Review article
AN - SCOPUS:85147829225
SN - 1754-6605
VL - 16
JO - ecancermedicalscience
JF - ecancermedicalscience
M1 - 1461
ER -