Fuzzy control of baseline activity within the basal ganglia of rat brain

M. Z. Ozair; S. Enam-Ur-Rehman; S. A. Enam

doi:10.1109/INMIC.2003.1416749

Fuzzy control of baseline activity within the basal ganglia of rat brain

M. Z. Ozair
, S. Enam-Ur-Rehman
, S. A. Enam

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

Deep brain stimulation (DBS) is an increasingly popular treatment modality for Parkinson's disease (PD) based on chronic electrical stimulation of the basal ganglia. The basal ganglia are responsible for regulating motor control of the human body, a function exemplified by disease states such as PD. We describe a novel technique based on a chronically implantable neural prosthetic device that could be used as a potential treatment in many basal ganglia disorders, including PD. The prosthetic device implements a fuzzy control of the baseline excitation of the motor cortex and derives a feedback loop from the thalamocortical pathway, thus forming a closed loop control. It improves over DBS by being self-adjustable, thereby eradicating the need of repeated adjustments of various parameters of the excitatory signal(s). The neural prosthetic device can be implanted in a rat brain and the fuzzy control rule set be derived from in vitro organotypic slice culture models of the basal ganglia.

Original language	English (UK)
Title of host publication	Proceedings - INMIC 2003
Subtitle of host publication	IEEE 7th International Multi Topic Conference
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	351-353
Number of pages	3
ISBN (Electronic)	0780381831, 9780780381834
DOIs	https://doi.org/10.1109/INMIC.2003.1416749
Publication status	Published - 2003
Externally published	Yes
Event	7th IEEE International Multi Topic Conference, INMIC 2003 - Islamabad, Pakistan Duration: 8 Dec 2003 → 9 Dec 2003

Publication series

Name	Proceedings - INMIC 2003: IEEE 7th International Multi Topic Conference

Conference

Conference	7th IEEE International Multi Topic Conference, INMIC 2003
Country/Territory	Pakistan
City	Islamabad
Period	8/12/03 → 9/12/03

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Basal ganglia
Brain stimulation
Electrical stimulation
Fuzzy control
Humans
Motor drives
Neural prosthesis
Parkinson's disease
Prosthetics
Satellite broadcasting

Access to Document

10.1109/INMIC.2003.1416749

Cite this

Ozair, M. Z., Enam-Ur-Rehman, S., & Enam, S. A. (2003). Fuzzy control of baseline activity within the basal ganglia of rat brain. In Proceedings - INMIC 2003: IEEE 7th International Multi Topic Conference (pp. 351-353). Article 1416749 (Proceedings - INMIC 2003: IEEE 7th International Multi Topic Conference). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/INMIC.2003.1416749

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title = "Fuzzy control of baseline activity within the basal ganglia of rat brain",

abstract = "Deep brain stimulation (DBS) is an increasingly popular treatment modality for Parkinson's disease (PD) based on chronic electrical stimulation of the basal ganglia. The basal ganglia are responsible for regulating motor control of the human body, a function exemplified by disease states such as PD. We describe a novel technique based on a chronically implantable neural prosthetic device that could be used as a potential treatment in many basal ganglia disorders, including PD. The prosthetic device implements a fuzzy control of the baseline excitation of the motor cortex and derives a feedback loop from the thalamocortical pathway, thus forming a closed loop control. It improves over DBS by being self-adjustable, thereby eradicating the need of repeated adjustments of various parameters of the excitatory signal(s). The neural prosthetic device can be implanted in a rat brain and the fuzzy control rule set be derived from in vitro organotypic slice culture models of the basal ganglia.",

keywords = "Basal ganglia, Brain stimulation, Electrical stimulation, Fuzzy control, Humans, Motor drives, Neural prosthesis, Parkinson's disease, Prosthetics, Satellite broadcasting",

author = "Ozair, \{M. Z.\} and S. Enam-Ur-Rehman and Enam, \{S. A.\}",

note = "Publisher Copyright: {\textcopyright} 2003 IEEE.; 7th IEEE International Multi Topic Conference, INMIC 2003 ; Conference date: 08-12-2003 Through 09-12-2003",

year = "2003",

doi = "10.1109/INMIC.2003.1416749",

language = "English (UK)",

series = "Proceedings - INMIC 2003: IEEE 7th International Multi Topic Conference",

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Ozair, MZ, Enam-Ur-Rehman, S & Enam, SA 2003, Fuzzy control of baseline activity within the basal ganglia of rat brain. in Proceedings - INMIC 2003: IEEE 7th International Multi Topic Conference., 1416749, Proceedings - INMIC 2003: IEEE 7th International Multi Topic Conference, Institute of Electrical and Electronics Engineers Inc., pp. 351-353, 7th IEEE International Multi Topic Conference, INMIC 2003, Islamabad, Pakistan, 8/12/03. https://doi.org/10.1109/INMIC.2003.1416749

Fuzzy control of baseline activity within the basal ganglia of rat brain. / Ozair, M. Z.; Enam-Ur-Rehman, S.; Enam, S. A.
Proceedings - INMIC 2003: IEEE 7th International Multi Topic Conference. Institute of Electrical and Electronics Engineers Inc., 2003. p. 351-353 1416749 (Proceedings - INMIC 2003: IEEE 7th International Multi Topic Conference).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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KW - Motor drives

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KW - Satellite broadcasting

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Ozair MZ, Enam-Ur-Rehman S, Enam SA. Fuzzy control of baseline activity within the basal ganglia of rat brain. In Proceedings - INMIC 2003: IEEE 7th International Multi Topic Conference. Institute of Electrical and Electronics Engineers Inc. 2003. p. 351-353. 1416749. (Proceedings - INMIC 2003: IEEE 7th International Multi Topic Conference). doi: 10.1109/INMIC.2003.1416749

Fuzzy control of baseline activity within the basal ganglia of rat brain

Abstract

Publication series

Conference

UN SDGs

Keywords

Access to Document

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