Gastric corpus polyps associated with Proton Pump Inhibitors therapy

Javed Yakoob, Zaigham Abbas, Wasim Jafri, Zubair Ahmad

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


The prevalence of Gastroesophageal Reflux Disease (GERD) is rapidly rising in Asia. We describe here a case of 51 years old man who had surgery for esophageal leiomyoma and received long-term therapy with Proton Pump Inhibitors (PPIs) for persisting reflux symptoms. On Esophago-Gastroduodenoscopy (EGD) several sessile polyps were seen in the gastric corpus. Earlier EGD done 15 years back had not demonstrated those polyps. Sections revealed polypoid fragments of glandular epithelium with dilated glands and negative histology for H. pylori. Polymerase chain reaction for 16S ribosomal RNA gene (16S rRNA PCR) of H. pylori was also negative. This is the first report originating from an Asian country describing Fundal Gland Polyps (FGPs) in the corpus of stomach rather than fundus in a patient on long-term PPI therapy.

Original languageEnglish
Pages (from-to)172-173
Number of pages2
JournalJournal of the College of Physicians and Surgeons--Pakistan : JCPSP
Issue number3
Publication statusPublished - Mar 2008


  • Gastric corpus polyps
  • Gastroesophageal reflux disease
  • Proton pump inhibitors


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