Geneesmiddelen bij rookstop tijdens de zwangerschap

Translated title of the contribution: Pharmacological aids in smoking cessation during pregnancy

H. Boudrez, M. Temmerman

Research output: Contribution to journalReview articlepeer-review


Smoking in pregnancy implies multiple health hazards for the fetus and the baby. Therefore smoking cessation in pregnancy should be stimulated. Inadequate treatment of nicotine-dependence is one of the main causes of cessation failures. An adequate treatment of nicotine dependence has been proven to increase the success of cessation. For this purpose, pharmacological methods have a place in the treatment of nicotine dependence during pregnancy. A limited number of trials have studied the safety and efficiency of smoking cessation pharmacology in pregnancy. Some recommendations can be made. The potential noxious effects of nicotine substitution do not exceed the gains of a successful attempt to quit, which will be stimulated with these products. The daily consumption of cigarettes may determine the dose of nicotine substitution, rather than the more complex drug-monitoring procedure. In this context, the 16-hours-patches can be considered (instead of 24-hours-patches), besides the products which can be used on an intermittent base, matching the urges and cravings of the pregnant smoker. Bupropion is contra-indicated. When a woman is already on bupropion at the time of conception, it should be stopped, especially in case of pre-eclampsia, nausea and vomiting. Nicotine substitution, as well as bupropion may be used in breastfeeding women.

Translated title of the contributionPharmacological aids in smoking cessation during pregnancy
Original languageDutch
Pages (from-to)1606-1616
Number of pages11
JournalTijdschrift voor Geneeskunde
Issue number22
Publication statusPublished - 15 Nov 2006
Externally publishedYes


Dive into the research topics of 'Pharmacological aids in smoking cessation during pregnancy'. Together they form a unique fingerprint.

Cite this