Genotypic analysis of multidrug-resistant Salmonella enterica serovar Typhi, Kenya

Samuel Kariuki; Charles Gilks; Gutura Revathi; C. Anthony Hart

doi:10.3201/eid0606.000616

Genotypic analysis of multidrug-resistant Salmonella enterica serovar Typhi, Kenya

Samuel Kariuki, Charles Gilks, Gutura Revathi, C. Anthony Hart

Research output: Contribution to journal › Article › peer-review

44 Citations (Scopus)

Abstract

We report the emergence in Kenya during 1997-1999 of typhoid fever due to Salmonella enterica serovar Typhi resistant to ampicillin, tetracycline, chloramphenicol, streptomycin, and cotrimoxazole. Genotyping by pulsed-field gel electrophoresis of Xbal-digested chromosomal DNA yielded a single cluster. The multidrug-resistant S. Typhi were related to earlier drug-susceptible isolates but were unrelated to multidrug-resistant isolates from Asia.

Original language	English
Pages (from-to)	649-651
Number of pages	3
Journal	Emerging Infectious Diseases
Volume	6
Issue number	6
DOIs	https://doi.org/10.3201/eid0606.000616
Publication status	Published - 2000
Externally published	Yes

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abstract = "We report the emergence in Kenya during 1997-1999 of typhoid fever due to Salmonella enterica serovar Typhi resistant to ampicillin, tetracycline, chloramphenicol, streptomycin, and cotrimoxazole. Genotyping by pulsed-field gel electrophoresis of Xbal-digested chromosomal DNA yielded a single cluster. The multidrug-resistant S. Typhi were related to earlier drug-susceptible isolates but were unrelated to multidrug-resistant isolates from Asia.",

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AB - We report the emergence in Kenya during 1997-1999 of typhoid fever due to Salmonella enterica serovar Typhi resistant to ampicillin, tetracycline, chloramphenicol, streptomycin, and cotrimoxazole. Genotyping by pulsed-field gel electrophoresis of Xbal-digested chromosomal DNA yielded a single cluster. The multidrug-resistant S. Typhi were related to earlier drug-susceptible isolates but were unrelated to multidrug-resistant isolates from Asia.

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Genotypic analysis of multidrug-resistant Salmonella enterica serovar Typhi, Kenya

Abstract

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