Gestationeel hyperandrogenisme

Gestational hyperandrogenism is a rare condition with potentially severe consequences for the pregnant woman and her female fetus in terms of permanent virilisation. The two most common causes include luteomas and theca-lutein cysts of the ovary. The diagnosis is based on history taking, hormone analysis and imaging. The therapeutic possibilities to prevent virilisation of a female foetus are unfortunately very limited. An appropriate counselling of the parents concerning the limited antenatal treatment options and the possibility of post-natal corrective surgery of the external genitals of the affected female newborn remain crucial. A case report is presented, followed by a brief discussion of the diagnostic and therapeutic approach of this uncommon condition.