@article{f5fe7f61daf240439eccd3ffe033e5da,
title = "Global think tank on the clinical considerations and management of lipoprotein(a): The top questions and answers regarding what clinicians need to know",
abstract = "Evidence from Mendelian randomization studies suggest that lipoprotein(a) (Lp(a)) has a causal role in the development of atherosclerotic cardiovascular disease risk. However, guidelines and consensus statement recommendations vary regarding how clinicians should incorporate Lp(a) into patient care. To provide practical answers to key questions pertaining to Lp(a) that clinicians will find useful when assessing and treating patients, a global think tank was convened. Representatives from seven national and international stakeholder organizations answered questions that were focused on: Lp(a) measurement; ethnic, gender, and age considerations; factoring Lp(a) into risk assessment; and current and emerging treatment options for elevated Lp(a). This manuscript summarizes the finding from this global think tank. Areas requiring further investigation were identified, and the need to standardize reporting of Lp(a) levels to ensure harmonization and comparability across laboratories and research studies is emphasized.",
keywords = "Atherosclerotic cardiovascular disease, Hypercholesterolemia, Lipoprotein(a), Low-density lipoprotein",
author = "Virani, {Salim S.} and Koschinsky, {Marlys L.} and Lisa Maher and Anurag Mehta and Orringer, {Carl E.} and Santos, {Raul D.} and Shapiro, {Michael D.} and Saseen, {Joseph J.}",
note = "Funding Information: Abbott, Ache, Amgen, Amryt, Astra Zeneca, EMS, Esperion, Getz Pharma, Kowa, Hypera, MSD, Merck, Novartis, Novo-Nordisk, Pfizer, PTC Therapeutics, Roche and Sanofi. SV has received research support from the National Institutes of Health , Department of Veterans Affairs , World Heart Federation , Tahir and Jooma Family and honorarium from the American College of Cardiology in his role as the Associate Editor for Innovations ( acc.org ). MLK has received honoraria related to consulting, research and/or speaker activities from Ayma, Novartis, Abcentra, and Amgen. MDS has served on Scientific Advisory Boards with the following entities: Amgen, Novartis, Novo Nordisk. Funding Information: The following organizations participated in the Global Think Tank on the Clinical Considerations and Management of Lipoprotein(a), resulting in a series of deliverables including this consensus document to which each organization approves: Association of Black Cardiologists (ABC), American College of Cardiology (ACC), American Heart Association (AHA), European Atherosclerosis Society (EAS), International Atherosclerosis Society (IAS), National Lipid Association (NLA), and Preventive Cardiovascular Nurses Association (PCNA).Abbott, Ache, Amgen, Amryt, Astra Zeneca, EMS, Esperion, Getz Pharma, Kowa, Hypera, MSD, Merck, Novartis, Novo-Nordisk, Pfizer, PTC Therapeutics, Roche and Sanofi. SV has received research support from the National Institutes of Health, Department of Veterans Affairs, World Heart Federation, Tahir and Jooma Family and honorarium from the American College of Cardiology in his role as the Associate Editor for Innovations (acc.org). MLK has received honoraria related to consulting, research and/or speaker activities from Ayma, Novartis, Abcentra, and Amgen. MDS has served on Scientific Advisory Boards with the following entities: Amgen, Novartis, Novo Nordisk.We are grateful for the efforts of the planning committee (Co-Chairs: Joseph J. Saseen and Salim S. Virani; Members: Christie Ballantyne, Amina Resheidat, Marlys Koschinsky, and Carl Orringer), stakeholder representatives who participated in the Think Tank (Karol Watson [Association of Black Cardiologists], Michael Shapiro and Anum Saeed [American College of Cardiology], Eduardo Sanchez [American Heart Association], Lale Tokgӧzoğlu [European Atherosclerosis Society], Samia Mora and Raul Santos [International Atherosclerosis Society], and Lisa Maher [Preventive Cardiovascular Nurse Association]), and other participants (Christa Cobbaert, Zareen Farukhi, Anne Goldberg, Anurag Mehta, James Underberg, Huber Vesper, and Don Wilson). Publisher Copyright: {\textcopyright} 2022 The Authors",
year = "2022",
month = jul,
day = "1",
doi = "10.1016/j.pcad.2022.01.002",
language = "English",
volume = "73",
pages = "32--40",
journal = "Progress in Cardiovascular Diseases",
issn = "0033-0620",
publisher = "W.B. Saunders Ltd",
}
