Granulomatous gastritis: A diagnostic dilemma?

Lubna Kamani, K. Mumtaz, N. S. Azad, W. Jafri

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9 Citations (Scopus)


Granulomatous inflammation of the gastrointestinal tract is an uncommon entity; an aetiopathogenic diagnosis can be reached only by combining the morphological examination with clinical and laboratory investigations. We report two cases of granulomatous gastritis: a 27-year-old woman presenting with weight loss and a 55-year-old woman presenting with epigastric pain and vomiting. Upper oesophagastroduodenoscopy in these cases showed antral hyperaemia and histopathology showed non-caseating gastric granulomatous inflammation. Both the cases were extensively worked-up for possible tuberculosis (TB) as the patients lived in an endemic area, before starting steroids for the possibility of Crohn's disease (CD) . The first patient improved but the second patient had a flare of underlying undiagnosed TB. Granulomatous gastritis present a diagnostic challenge for treating physicians because of similar clinical, laboratory and endoscopical features between CD and intestinal TB.

Original languageEnglish
Pages (from-to)e222-e224
JournalSingapore Medical Journal
Issue number9
Publication statusPublished - Sept 2008


  • Crohn's disease
  • Enteritis
  • Gastritis
  • Gastrointestinal tract inflammation
  • Granulomatous gastritis
  • Tuberculosis


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