Graves' Disease and Pulmonary Hypertension: Report of 2 Cases

Salim S. Virani, Cesar E. Mendoza, Alexandre C. Ferreira, Eduardo De Marchena

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)


A possible association between hyperthyroidism and pulmonary hypertension has been reported. We describe 2 patients who had pulmonary hypertension associated with Graves' disease, both of whom experienced prompt hemodynamic and symptomatic recovery after normal thyroid function was restored. An autoimmune mechanism associated with vascular endothelial damage appears to have played a key pathogenic role in the development of pulmonary hypertension in these patients.

Original languageEnglish
Pages (from-to)314-315
Number of pages2
JournalTexas Heart Institute Journal
Issue number4
Publication statusPublished - 2003
Externally publishedYes


  • Autoimmune diseases/complications
  • Endothelium, vascular/injury
  • Graves' disease/complications/drug therapy
  • Hypertension, pulmonary
  • Hyperthyroidism/complications


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