Haemodynamic effects of intrathecal Bupivacaine for surgical repair of hip fracture

Mohammad Qamarul Hoda, Sabir Saeed, Gauhar Afshan, Salman Sabir

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)


Objective: To determine the optimal dose of bupivacaine in providing adequate surgical anaesthesia with minimal haemodynamic disturbances. Methods: Three different doses of spinal bupivacaine in combination with or without fentanyl for surgical repair of hip fracture were used. Sixty patients were randomly divided into three groups (A, B and C) to receive a spinal anaesthetic of bupivacaine 10mg, 8mg and 6mg respectively. In addition to bupivacaine, group B and C also received fentanyl 20μg in spinal mixture. Results: Intra operative heart rate was statistically insignificant in all three groups. Statistically significant drop in systolic blood pressure was found in group A & B at different study timings while statistically significant drop in diastolic blood pressure was only found in group A. Sensory block characteristics were similar among all three groups. Motor block pattern was found marginally significant in group C with highest time to achieve desired block. All patients had satisfactory level of surgical anaesthesia. Conclusion: This study concluded that low dose, 6mg bupivacaine with 20μg fentanyl provide adequate anaesthesia for surgical repair of hip fracture with stable haemodynamics.

Original languageEnglish
Pages (from-to)245-248
Number of pages4
JournalJournal of the Pakistan Medical Association
Issue number5
Publication statusPublished - May 2007


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