Abstract
Background: The prevalence and incidence of Helicobacter pylori in children in Pakistan is not known.Objectives: To measure the prevalence and age of acquisition of Helicobacter pylori infection/colonization in infants in a peri-urban community in Karachi, Pakistan.SETTING: Field based epidemiologic study in a peri-urban community in Karachi, Pakistan.Methods: Infants aged 1 to 3 months were recruited from a birth cohort from the community. C-urea breath test (C-UBT) was performed on recruitment, and the test was repeated at 2, 3, 6, and 9 months of age.Results: One hundred forty-eight infants were recruited and had C-UBT on 319 occasions over a period of 2 years. Two hundred thirty-one=(72%) tests were positive: 80% (49/61) infants at 1 month of age, 79% (33/42) at 2 month of age, 76% (92/121) at 3 month of age, 58% (37/64) at 6 months of age, and 67% (20/30) at 9 months of age.CONCLUSIONS: The study reveals an early colonization/infection of infants and a high prevalence of Helicobacter pylori in a peri-urban community in Karachi, Pakistan.
| Original language | Undefined/Unknown |
|---|---|
| Pages (from-to) | 191-194 |
| Number of pages | 4 |
| Journal | Journal of Pediatric Gastroenterology and Nutrition |
| Volume | 41 |
| Issue number | 2 |
| Publication status | Published - 1 Aug 2005 |
Keywords
- C-UBT
- Helicobacter pylori
- Infants
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