Helicobacter species ribosomal DNA recovered from the liver tissue of chinese patients with primary hepatocellular carcinoma

Xue Gong Fan; Xiao Ning Peng; Yan Huang; Javed Yakoob; Zhi Ming Wang; Yong Ping Chen

doi:10.1086/344770

Helicobacter species ribosomal DNA recovered from the liver tissue of chinese patients with primary hepatocellular carcinoma

Xue Gong Fan, Xiao Ning Peng, Yan Huang, Javed Yakoob, Zhi Ming Wang, Yong Ping Chen

Research output: Contribution to journal › Article › peer-review

39 Citations (Scopus)

Abstract

Using polymerase chain reaction (PCR), we examined 16S ribosomal DNA (rDNA) of Helicobacter species in liver tissue specimens obtained from 15 patients with hepatocellular carcinoma. Sixty percent (9 of 15) of these specimens were found to be positive for Helicobacter species. Four 16S rDNA fragments from positive PCR samples were directly sequenced. By sequence comparison, all were found to be 99% identical to the 16S rRNA of Helicobacter pylori.

Original language	English
Pages (from-to)	1555-1557
Number of pages	3
Journal	Clinical Infectious Diseases
Volume	35
Issue number	12
DOIs	https://doi.org/10.1086/344770
Publication status	Published - 15 Dec 2002
Externally published	Yes

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abstract = "Using polymerase chain reaction (PCR), we examined 16S ribosomal DNA (rDNA) of Helicobacter species in liver tissue specimens obtained from 15 patients with hepatocellular carcinoma. Sixty percent (9 of 15) of these specimens were found to be positive for Helicobacter species. Four 16S rDNA fragments from positive PCR samples were directly sequenced. By sequence comparison, all were found to be 99% identical to the 16S rRNA of Helicobacter pylori.",

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AU - Peng, Xiao Ning

AU - Huang, Yan

AU - Yakoob, Javed

AU - Wang, Zhi Ming

AU - Chen, Yong Ping

PY - 2002/12/15

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AB - Using polymerase chain reaction (PCR), we examined 16S ribosomal DNA (rDNA) of Helicobacter species in liver tissue specimens obtained from 15 patients with hepatocellular carcinoma. Sixty percent (9 of 15) of these specimens were found to be positive for Helicobacter species. Four 16S rDNA fragments from positive PCR samples were directly sequenced. By sequence comparison, all were found to be 99% identical to the 16S rRNA of Helicobacter pylori.

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Helicobacter species ribosomal DNA recovered from the liver tissue of chinese patients with primary hepatocellular carcinoma

Abstract

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