Hepatitis C at presentation in a newly diagnosed infant with B Acute Lymphoblastic Leukemia

Qurratulain Shahood Ahmed; Zehra Fadoo; Kamran Sadiq; Sadaf Altaf

doi:10.1016/j.phoj.2017.11.003

Hepatitis C at presentation in a newly diagnosed infant with B Acute Lymphoblastic Leukemia

Qurratulain Shahood Ahmed, Zehra Fadoo, Kamran Sadiq, Sadaf Altaf

Research output: Contribution to journal › Article › peer-review

Abstract

We report the unique case of a nine-month old patient diagnosed with B- Cell Acute Lymphoblastic Leukemia also positive for Hepatitis C virus, genotype 3 and a high viral load. With no existent literature to guide treatment of Hepatitis C in context of Infant Leukemia, treatment with direct-acting antivirals was deferred. A conservative approach to Hepatitis C was sought while he was undergoing chemotherapy, with the expectation of a spontaneous viral clearance, as has been documented for a quarter of otherwise healthy infants.

Original language	English (UK)
Pages (from-to)	31-33
Number of pages	3
Journal	Pediatric Hematology Oncology Journal
Volume	3
Issue number	1
DOIs	https://doi.org/10.1016/j.phoj.2017.11.003
Publication status	Published - Mar 2018

Keywords

Direct acting antivirals
Hepatitis C
Infant leukemia

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.phoj.2017.11.003

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title = "Hepatitis C at presentation in a newly diagnosed infant with B Acute Lymphoblastic Leukemia",

abstract = "We report the unique case of a nine-month old patient diagnosed with B- Cell Acute Lymphoblastic Leukemia also positive for Hepatitis C virus, genotype 3 and a high viral load. With no existent literature to guide treatment of Hepatitis C in context of Infant Leukemia, treatment with direct-acting antivirals was deferred. A conservative approach to Hepatitis C was sought while he was undergoing chemotherapy, with the expectation of a spontaneous viral clearance, as has been documented for a quarter of otherwise healthy infants.",

keywords = "Direct acting antivirals, Hepatitis C, Infant leukemia",

author = "Ahmed, \{Qurratulain Shahood\} and Zehra Fadoo and Kamran Sadiq and Sadaf Altaf",

note = "Publisher Copyright: {\textcopyright} 2017 Pediatric Hematology Oncology Chapter of Indian Academy of Pediatrics",

year = "2018",

month = mar,

doi = "10.1016/j.phoj.2017.11.003",

language = "English (UK)",

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AU - Ahmed, Qurratulain Shahood

AU - Fadoo, Zehra

AU - Sadiq, Kamran

AU - Altaf, Sadaf

PY - 2018/3

Y1 - 2018/3

N2 - We report the unique case of a nine-month old patient diagnosed with B- Cell Acute Lymphoblastic Leukemia also positive for Hepatitis C virus, genotype 3 and a high viral load. With no existent literature to guide treatment of Hepatitis C in context of Infant Leukemia, treatment with direct-acting antivirals was deferred. A conservative approach to Hepatitis C was sought while he was undergoing chemotherapy, with the expectation of a spontaneous viral clearance, as has been documented for a quarter of otherwise healthy infants.

AB - We report the unique case of a nine-month old patient diagnosed with B- Cell Acute Lymphoblastic Leukemia also positive for Hepatitis C virus, genotype 3 and a high viral load. With no existent literature to guide treatment of Hepatitis C in context of Infant Leukemia, treatment with direct-acting antivirals was deferred. A conservative approach to Hepatitis C was sought while he was undergoing chemotherapy, with the expectation of a spontaneous viral clearance, as has been documented for a quarter of otherwise healthy infants.

KW - Direct acting antivirals

KW - Hepatitis C

KW - Infant leukemia

UR - https://www.scopus.com/pages/publications/85157063674

U2 - 10.1016/j.phoj.2017.11.003

DO - 10.1016/j.phoj.2017.11.003

M3 - Article

AN - SCOPUS:85157063674

SN - 2468-1245

VL - 3

SP - 31

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JO - Pediatric Hematology Oncology Journal

JF - Pediatric Hematology Oncology Journal

IS - 1

ER -

Hepatitis C at presentation in a newly diagnosed infant with B Acute Lymphoblastic Leukemia

Abstract

Keywords

UN SDGs

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