Hepatitis C elimination: is it time to redefine the goals?

Yasser Fouad; Ming Lung Yu; Saeed Hamid; Robert G. Gish; Mohammed Eslam

doi:10.1038/s41575-026-01184-x

Hepatitis C elimination: is it time to redefine the goals?

Yasser Fouad
, Ming Lung Yu
, Saeed Hamid
, Robert G. Gish
, Mohammed Eslam

Department of Medicine, Medical College, Pakistan

Research output: Contribution to journal › Comment/debate

Abstract

Direct-acting antiviral agents have substantially improved the rate of sustained virologic response and safety in the treatment of hepatitis C. However, concerns about the long-term outcomes for individuals who achieve sustained virologic response still exist. Herein, we propose a new conceptual model for redefining the goals and strategies of ongoing hepatitis C elimination campaigns.

Original language	English (US)
Journal	Nature Reviews Gastroenterology and Hepatology
DOIs	https://doi.org/10.1038/s41575-026-01184-x
Publication status	Accepted/In press - 2026

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1038/s41575-026-01184-x

Cite this

@article{c7888a8a1a7b4de8963dd51eb45063e7,

title = "Hepatitis C elimination: is it time to redefine the goals?",

abstract = "Direct-acting antiviral agents have substantially improved the rate of sustained virologic response and safety in the treatment of hepatitis C. However, concerns about the long-term outcomes for individuals who achieve sustained virologic response still exist. Herein, we propose a new conceptual model for redefining the goals and strategies of ongoing hepatitis C elimination campaigns.",

author = "Yasser Fouad and Yu, \{Ming Lung\} and Saeed Hamid and Gish, \{Robert G.\} and Mohammed Eslam",

note = "Publisher Copyright: {\textcopyright} Springer Nature Limited 2026.",

year = "2026",

doi = "10.1038/s41575-026-01184-x",

language = "English (US)",

journal = "Nature Reviews Gastroenterology and Hepatology",

issn = "1759-5045",

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TY - JOUR

T1 - Hepatitis C elimination

T2 - is it time to redefine the goals?

AU - Fouad, Yasser

AU - Yu, Ming Lung

AU - Hamid, Saeed

AU - Gish, Robert G.

AU - Eslam, Mohammed

PY - 2026

Y1 - 2026

N2 - Direct-acting antiviral agents have substantially improved the rate of sustained virologic response and safety in the treatment of hepatitis C. However, concerns about the long-term outcomes for individuals who achieve sustained virologic response still exist. Herein, we propose a new conceptual model for redefining the goals and strategies of ongoing hepatitis C elimination campaigns.

AB - Direct-acting antiviral agents have substantially improved the rate of sustained virologic response and safety in the treatment of hepatitis C. However, concerns about the long-term outcomes for individuals who achieve sustained virologic response still exist. Herein, we propose a new conceptual model for redefining the goals and strategies of ongoing hepatitis C elimination campaigns.

UR - https://www.scopus.com/pages/publications/105031095490

U2 - 10.1038/s41575-026-01184-x

DO - 10.1038/s41575-026-01184-x

M3 - Comment/debate

C2 - 41731055

AN - SCOPUS:105031095490

SN - 1759-5045

JO - Nature Reviews Gastroenterology and Hepatology

JF - Nature Reviews Gastroenterology and Hepatology

ER -

Hepatitis C elimination: is it time to redefine the goals?

Abstract

UN SDGs

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