High frequency of blackwater fever among children presenting to hospital with fevere febrile illnesses in eastern Uganda.

Ssenkusu John Mbaziira; Hodges James Steven; Robert Opoka; Idro Richard; Shapiro Esther; John Chandy Chiramukhathu; Bangirana Paul

doi:10.1542/peds.2016-1965

High frequency of blackwater fever among children presenting to hospital with fevere febrile illnesses in eastern Uganda.

Ssenkusu John Mbaziira
, Hodges James Steven
, Robert Opoka
, Idro Richard
, Shapiro Esther
, John Chandy Chiramukhathu
, Bangirana Paul

Medical College, East Africa

Research output: Contribution to journal › Article

46 Citations (Scopus)

Abstract

BACKGROUND: Severe malaria in children is associated with long-term neurocognitive a impairment, but it is unclear whether it is associated with long-term behavioral problems.

METHODS: Children

RESULTS: At 12 months, children with SMA had higher z-scores than CC children for internalizing (mean difference, 0.49; SE, 0.14; P = .001), externalizing (mean difference, 0.49; SE, 0.15; P = .001), and total problems (mean difference, 0.51; SE, 0.15; P < .001). Children with CM had higher adjusted z-scores than CC children for externalizing problems (mean difference, 0.39; SE, 0.15; P = .009) but not internalizing or total problems. At 24 months, children with CM or SMA both had increased internalizing and externalizing behavioral problems compared with CC children (P ≤ .05 for all).

CONCLUSIONS: CM and SMA are associated with long-term internalizing and externalizing behavioral problems in children. They may contribute substantially to mental health morbidity in children

Original language	Undefined/Unknown
Journal	Paediatrics and Child Health, East Africa
DOIs	https://doi.org/10.1542/peds.2016-1965
Publication status	Published - 1 Dec 2017

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1542/peds.2016-1965Licence: Unspecified

http://ecommons.aku.edu/eastafrica_fhs_mc_paediatr_child_health/513

Cite this

@article{f604337c0648441285a43f9dc20b339a,

title = "High frequency of blackwater fever among children presenting to hospital with fevere febrile illnesses in eastern Uganda.",

abstract = "BACKGROUND: Severe malaria in children is associated with long-term neurocognitive a impairment, but it is unclear whether it is associated with long-term behavioral problems. METHODS: Children RESULTS: At 12 months, children with SMA had higher z-scores than CC children for internalizing (mean difference, 0.49; SE, 0.14; P = .001), externalizing (mean difference, 0.49; SE, 0.15; P = .001), and total problems (mean difference, 0.51; SE, 0.15; P < .001). Children with CM had higher adjusted z-scores than CC children for externalizing problems (mean difference, 0.39; SE, 0.15; P = .009) but not internalizing or total problems. At 24 months, children with CM or SMA both had increased internalizing and externalizing behavioral problems compared with CC children (P ≤ .05 for all). CONCLUSIONS: CM and SMA are associated with long-term internalizing and externalizing behavioral problems in children. They may contribute substantially to mental health morbidity in children",

author = "Mbaziira, \{Ssenkusu John\} and Steven, \{Hodges James\} and Robert Opoka and Idro Richard and Shapiro Esther and Chiramukhathu, \{John Chandy\} and Bangirana Paul",

year = "2017",

month = dec,

day = "1",

doi = "10.1542/peds.2016-1965",

language = "Undefined/Unknown",

journal = "Paediatrics and Child Health, East Africa",

}

TY - JOUR

T1 - High frequency of blackwater fever among children presenting to hospital with fevere febrile illnesses in eastern Uganda.

AU - Mbaziira, Ssenkusu John

AU - Steven, Hodges James

AU - Opoka, Robert

AU - Richard, Idro

AU - Esther, Shapiro

AU - Chiramukhathu, John Chandy

AU - Paul, Bangirana

PY - 2017/12/1

Y1 - 2017/12/1

N2 - BACKGROUND: Severe malaria in children is associated with long-term neurocognitive a impairment, but it is unclear whether it is associated with long-term behavioral problems. METHODS: Children RESULTS: At 12 months, children with SMA had higher z-scores than CC children for internalizing (mean difference, 0.49; SE, 0.14; P = .001), externalizing (mean difference, 0.49; SE, 0.15; P = .001), and total problems (mean difference, 0.51; SE, 0.15; P < .001). Children with CM had higher adjusted z-scores than CC children for externalizing problems (mean difference, 0.39; SE, 0.15; P = .009) but not internalizing or total problems. At 24 months, children with CM or SMA both had increased internalizing and externalizing behavioral problems compared with CC children (P ≤ .05 for all). CONCLUSIONS: CM and SMA are associated with long-term internalizing and externalizing behavioral problems in children. They may contribute substantially to mental health morbidity in children

AB - BACKGROUND: Severe malaria in children is associated with long-term neurocognitive a impairment, but it is unclear whether it is associated with long-term behavioral problems. METHODS: Children RESULTS: At 12 months, children with SMA had higher z-scores than CC children for internalizing (mean difference, 0.49; SE, 0.14; P = .001), externalizing (mean difference, 0.49; SE, 0.15; P = .001), and total problems (mean difference, 0.51; SE, 0.15; P < .001). Children with CM had higher adjusted z-scores than CC children for externalizing problems (mean difference, 0.39; SE, 0.15; P = .009) but not internalizing or total problems. At 24 months, children with CM or SMA both had increased internalizing and externalizing behavioral problems compared with CC children (P ≤ .05 for all). CONCLUSIONS: CM and SMA are associated with long-term internalizing and externalizing behavioral problems in children. They may contribute substantially to mental health morbidity in children

U2 - 10.1542/peds.2016-1965

DO - 10.1542/peds.2016-1965

M3 - Article

JO - Paediatrics and Child Health, East Africa

JF - Paediatrics and Child Health, East Africa

ER -