Hyper-reactive malarial splenomegaly in the absence of raised IgM antibodies

Mahnur Haider; Sobia Nizami; Adnan Qureshi; Afsheen Raza; Farheen Karim Mahar; Mohammad Asim Beg

doi:10.1177/0049475512473602

Hyper-reactive malarial splenomegaly in the absence of raised IgM antibodies

Mahnur Haider, Sobia Nizami, Adnan Qureshi, Afsheen Raza, Farheen Karim Mahar, Mohammad Asim Beg

Department of Pathology and Laboratory Medicine, Medical College, Pakistan

Research output: Contribution to journal › Review article › peer-review

1 Citation (Scopus)

Abstract

Hyper-reactivemalarial splenomegaly (HMS) is diagnosed by the presence of massive splenomegaly, raised IgM and antimalarial antibodies and a response to antimalarial therapy. Althoughmalaria is endemic to Pakistan, HMS is uncommon.We report onHMS in a patient withmassive splenomegaly, positive Plasmodium falciparum polymerase chain reaction but normal immunoglobulinMantibody levels.The investigations were not consistent with any other diagnosis. HMS is also briefly reviewed.

Original language	English
Pages (from-to)	37-38
Number of pages	2
Journal	Tropical Doctor
Volume	43
Issue number	1
DOIs	https://doi.org/10.1177/0049475512473602
Publication status	Published - Jan 2013

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abstract = "Hyper-reactivemalarial splenomegaly (HMS) is diagnosed by the presence of massive splenomegaly, raised IgM and antimalarial antibodies and a response to antimalarial therapy. Althoughmalaria is endemic to Pakistan, HMS is uncommon.We report onHMS in a patient withmassive splenomegaly, positive Plasmodium falciparum polymerase chain reaction but normal immunoglobulinMantibody levels.The investigations were not consistent with any other diagnosis. HMS is also briefly reviewed.",

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AU - Haider, Mahnur

AU - Nizami, Sobia

AU - Qureshi, Adnan

AU - Raza, Afsheen

AU - Mahar, Farheen Karim

AU - Beg, Mohammad Asim

PY - 2013/1

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N2 - Hyper-reactivemalarial splenomegaly (HMS) is diagnosed by the presence of massive splenomegaly, raised IgM and antimalarial antibodies and a response to antimalarial therapy. Althoughmalaria is endemic to Pakistan, HMS is uncommon.We report onHMS in a patient withmassive splenomegaly, positive Plasmodium falciparum polymerase chain reaction but normal immunoglobulinMantibody levels.The investigations were not consistent with any other diagnosis. HMS is also briefly reviewed.

AB - Hyper-reactivemalarial splenomegaly (HMS) is diagnosed by the presence of massive splenomegaly, raised IgM and antimalarial antibodies and a response to antimalarial therapy. Althoughmalaria is endemic to Pakistan, HMS is uncommon.We report onHMS in a patient withmassive splenomegaly, positive Plasmodium falciparum polymerase chain reaction but normal immunoglobulinMantibody levels.The investigations were not consistent with any other diagnosis. HMS is also briefly reviewed.

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Hyper-reactive malarial splenomegaly in the absence of raised IgM antibodies

Abstract

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