Hyper-reactive malarial splenomegaly in the absence of raised IgM antibodies

Mahnur Haider, Sobia Nizami, Adnan Qureshi, Afsheen Raza, Farheen Karim Mahar, Mohammad Asim Beg

Research output: Contribution to journalReview articlepeer-review

1 Citation (Scopus)


Hyper-reactivemalarial splenomegaly (HMS) is diagnosed by the presence of massive splenomegaly, raised IgM and antimalarial antibodies and a response to antimalarial therapy. Althoughmalaria is endemic to Pakistan, HMS is uncommon.We report onHMS in a patient withmassive splenomegaly, positive Plasmodium falciparum polymerase chain reaction but normal immunoglobulinMantibody levels.The investigations were not consistent with any other diagnosis. HMS is also briefly reviewed.

Original languageEnglish
Pages (from-to)37-38
Number of pages2
JournalTropical Doctor
Issue number1
Publication statusPublished - Jan 2013


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