Abstract
The etiology of common idiopathic epileptic syndromes is genetically determined, but the complex pattern of inheritance suggests an epistatic interaction of several susceptibility genes. Mutations in over 70 genes now define biological pathways leading to rare monogenic forms of epilepsy in humans and animals. Recognizing the molecular basis of an ion-channel disease has provided new opportunities for screenirig, early diagnosis, and therapy of these conditions.
| Original language | English |
|---|---|
| Pages (from-to) | 415-418 |
| Number of pages | 4 |
| Journal | Journal of the Pakistan Medical Association |
| Volume | 57 |
| Issue number | 8 |
| Publication status | Published - Aug 2007 |