Idiopathic epilepsy of childhood and potassium ion channels

Alper I. Dai, Mohammad Wasay

Research output: Contribution to journalReview articlepeer-review

4 Citations (Scopus)


The etiology of common idiopathic epileptic syndromes is genetically determined, but the complex pattern of inheritance suggests an epistatic interaction of several susceptibility genes. Mutations in over 70 genes now define biological pathways leading to rare monogenic forms of epilepsy in humans and animals. Recognizing the molecular basis of an ion-channel disease has provided new opportunities for screenirig, early diagnosis, and therapy of these conditions.

Original languageEnglish
Pages (from-to)415-418
Number of pages4
JournalJournal of the Pakistan Medical Association
Issue number8
Publication statusPublished - Aug 2007


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