Immune and endothelial activation markers and risk stratification of childhood pneumonia in Uganda: A secondary analysis of a prospective cohort study

Chloe McDonald, Aleksandra Leligdowicz, Andrea Conroy, Andrea Weckman, Melissa Richard-Greenblatt, Michelle Ngai, Clara Erice, Kathleen Zhong, Sophie Namasopo, Robert Opoka

Research output: Contribution to journalArticle

Abstract

Despite the global burden of pneumonia, reliable triage tools to identify children in low-resource settings at risk of severe and fatal respiratory tract infection are lacking. This study assessed the ability of circulating host markers of immune and endothelial activation quantified at presentation, relative to currently used clinical measures of disease severity, to identify children with pneumonia who are at risk of death.

Original languageUndefined/Unknown
JournalPaediatrics and Child Health, East Africa
Publication statusPublished - 1 Jul 2022

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