Implementation of single-dose nevirapine for prevention of MTCT of HIV - lessons from Cape Town : scientific letter

Marleen Temmerman; Wim Delva; Beverly Draper

Implementation of single-dose nevirapine for prevention of MTCT of HIV - lessons from Cape Town : scientific letter

Marleen Temmerman, Wim Delva, Beverly Draper

Centre of Excellence in Women and Child Health, East Africa

Research output: Contribution to journal › Article

Abstract

The HIVNET 012 study1 in Uganda demonstrated the efficacy of the single-dose nevirapine regimen in prevention of mother-to-child transmission (PMTCT) of HIV in developing countries. However, recent reports of implementation studies in Kenya, Botswana, Zimbabwe and West Africa show that there may be an important gap between the efficacy in clinical trial circumstances and the effectiveness of PMTCT programmes when implemented in field conditions.2-7 Return rates for test results and collection of the drugs, adherence to infant feeding recommendations and the antiretroviral drug regimen and follow-up turned out to be suboptimal, thereby limiting the ..

Original language	Undefined/Unknown
Journal	Faculty of Health Sciences, East Africa
Publication status	Published - 1 Aug 2006

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http://ecommons.aku.edu/eastafrica_fhs_fhs/380

Cite this

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abstract = "The HIVNET 012 study1 in Uganda demonstrated the efficacy of the single-dose nevirapine regimen in prevention of mother-to-child transmission (PMTCT) of HIV in developing countries. However, recent reports of implementation studies in Kenya, Botswana, Zimbabwe and West Africa show that there may be an important gap between the efficacy in clinical trial circumstances and the effectiveness of PMTCT programmes when implemented in field conditions.2-7 Return rates for test results and collection of the drugs, adherence to infant feeding recommendations and the antiretroviral drug regimen and follow-up turned out to be suboptimal, thereby limiting the ..",

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AU - Draper, Beverly

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N2 - The HIVNET 012 study1 in Uganda demonstrated the efficacy of the single-dose nevirapine regimen in prevention of mother-to-child transmission (PMTCT) of HIV in developing countries. However, recent reports of implementation studies in Kenya, Botswana, Zimbabwe and West Africa show that there may be an important gap between the efficacy in clinical trial circumstances and the effectiveness of PMTCT programmes when implemented in field conditions.2-7 Return rates for test results and collection of the drugs, adherence to infant feeding recommendations and the antiretroviral drug regimen and follow-up turned out to be suboptimal, thereby limiting the ..

AB - The HIVNET 012 study1 in Uganda demonstrated the efficacy of the single-dose nevirapine regimen in prevention of mother-to-child transmission (PMTCT) of HIV in developing countries. However, recent reports of implementation studies in Kenya, Botswana, Zimbabwe and West Africa show that there may be an important gap between the efficacy in clinical trial circumstances and the effectiveness of PMTCT programmes when implemented in field conditions.2-7 Return rates for test results and collection of the drugs, adherence to infant feeding recommendations and the antiretroviral drug regimen and follow-up turned out to be suboptimal, thereby limiting the ..

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