Incidental MRI lesions suggestive of multiple sclerosis in asymptomatic patients in Karachi, Pakistan

M. Wasay; F. Rizvi; M. Azeemuddin; A. Yousuf; S. Fredrikson

doi:10.1136/jnnp.2009.180000

Incidental MRI lesions suggestive of multiple sclerosis in asymptomatic patients in Karachi, Pakistan

M. Wasay
, F. Rizvi
, M. Azeemuddin
, A. Yousuf
, S. Fredrikson

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

Abstract

The objective of this study was to identify asymptomatic patients with brain MRI lesions suggestive of multiple sclerosis (MS) in a low-prevalence area of Pakistan. Brain MRIs for 864 patients were reviewed at the Aga Khan University (Karachi, Pakistan) during an 8-month period of 2006 and 2007 to identify patients with lesions suggestive of MS. The lesions were characterised based on modified Barkhof criteria. Six (two females) (0.7%) of 864 patients fulfilled brain MRI criteria suggestive of MS. The mean number of MRI lesions (total lesions on T2) were 9 (range 5e14). Although Pakistan is considered a low-prevalence area for MS, 0.7% of brain MRI scans in patients without clinical MS symptoms showed lesions fulfilling brain MRI criteria of MS.

Original language	English (UK)
Pages (from-to)	83-86
Number of pages	4
Journal	Journal of Neurology, Neurosurgery and Psychiatry
Volume	82
Issue number	1
DOIs	https://doi.org/10.1136/jnnp.2009.180000
Publication status	Published - Jan 2011

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1136/jnnp.2009.180000

Cite this

@article{a4de34b5d21d428497fc150c1adce936,

title = "Incidental MRI lesions suggestive of multiple sclerosis in asymptomatic patients in Karachi, Pakistan",

abstract = "The objective of this study was to identify asymptomatic patients with brain MRI lesions suggestive of multiple sclerosis (MS) in a low-prevalence area of Pakistan. Brain MRIs for 864 patients were reviewed at the Aga Khan University (Karachi, Pakistan) during an 8-month period of 2006 and 2007 to identify patients with lesions suggestive of MS. The lesions were characterised based on modified Barkhof criteria. Six (two females) (0.7\%) of 864 patients fulfilled brain MRI criteria suggestive of MS. The mean number of MRI lesions (total lesions on T2) were 9 (range 5e14). Although Pakistan is considered a low-prevalence area for MS, 0.7\% of brain MRI scans in patients without clinical MS symptoms showed lesions fulfilling brain MRI criteria of MS.",

author = "M. Wasay and F. Rizvi and M. Azeemuddin and A. Yousuf and S. Fredrikson",

year = "2011",

month = jan,

doi = "10.1136/jnnp.2009.180000",

language = "English (UK)",

volume = "82",

pages = "83--86",

journal = "Journal of Neurology, Neurosurgery and Psychiatry",

issn = "0022-3050",

publisher = "BMJ Publishing Group",

number = "1",

}

TY - JOUR

T1 - Incidental MRI lesions suggestive of multiple sclerosis in asymptomatic patients in Karachi, Pakistan

AU - Wasay, M.

AU - Rizvi, F.

AU - Azeemuddin, M.

AU - Yousuf, A.

AU - Fredrikson, S.

PY - 2011/1

Y1 - 2011/1

N2 - The objective of this study was to identify asymptomatic patients with brain MRI lesions suggestive of multiple sclerosis (MS) in a low-prevalence area of Pakistan. Brain MRIs for 864 patients were reviewed at the Aga Khan University (Karachi, Pakistan) during an 8-month period of 2006 and 2007 to identify patients with lesions suggestive of MS. The lesions were characterised based on modified Barkhof criteria. Six (two females) (0.7%) of 864 patients fulfilled brain MRI criteria suggestive of MS. The mean number of MRI lesions (total lesions on T2) were 9 (range 5e14). Although Pakistan is considered a low-prevalence area for MS, 0.7% of brain MRI scans in patients without clinical MS symptoms showed lesions fulfilling brain MRI criteria of MS.

AB - The objective of this study was to identify asymptomatic patients with brain MRI lesions suggestive of multiple sclerosis (MS) in a low-prevalence area of Pakistan. Brain MRIs for 864 patients were reviewed at the Aga Khan University (Karachi, Pakistan) during an 8-month period of 2006 and 2007 to identify patients with lesions suggestive of MS. The lesions were characterised based on modified Barkhof criteria. Six (two females) (0.7%) of 864 patients fulfilled brain MRI criteria suggestive of MS. The mean number of MRI lesions (total lesions on T2) were 9 (range 5e14). Although Pakistan is considered a low-prevalence area for MS, 0.7% of brain MRI scans in patients without clinical MS symptoms showed lesions fulfilling brain MRI criteria of MS.

UR - https://www.scopus.com/pages/publications/78650517228

U2 - 10.1136/jnnp.2009.180000

DO - 10.1136/jnnp.2009.180000

M3 - Article

AN - SCOPUS:78650517228

SN - 0022-3050

VL - 82

SP - 83

EP - 86

JO - Journal of Neurology, Neurosurgery and Psychiatry

JF - Journal of Neurology, Neurosurgery and Psychiatry

IS - 1

ER -

Incidental MRI lesions suggestive of multiple sclerosis in asymptomatic patients in Karachi, Pakistan

Abstract

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this