@inproceedings{fce303f45e3d441abacb62ca89381ce4,
title = "Infrastructuring transdisciplinary problem solving in translational research",
abstract = "Translational Research in the health sciences endeavors to bring biomedical discoveries into clinical applications that improve human health. This work is complex and long-term with a substantial risk of failure. A key step of clinical trials is needed to evaluate the effects of those interventions on human biomedical or behavioral outcomes. Timely recruitment of human subjects and meeting recruitment milestones is recognized as one of the most significant contributors to delays and failures. Quality and Design approaches have been tried to address the problem but the scope has been limited. We proposed to determine how Quality and Design may lead to complementary solutions for these barriers of Translational Research. The first ten studios using this approach are presented here. Three themes emerged: (1) problems were investigated similarly but there was a difference in insights, (2) quality process-based solutions tended to be specific to the issue discussed whereas the design process often yielded solutions broader or even tangential, and (3) quality solutions demonstrated more immediacy while design solutions showed more systemic ideas. In conclusion, the paper demonstrates how Design and Quality in a transdisciplinary studio may lead to solutions with different characteristics for clinical trials and advance translational science.",
keywords = "Clinical trials, Design approach, Human centered design, Quality approach, Systems design, Transdisciplinary methods, Translation, Translational science",
author = "Santosh Basapur and Keiichi Sato and Shah, {Raj C.} and Sherry Robison",
note = "Publisher Copyright: {\textcopyright} 2021 The authors and IOS Press.; 28th ISTE International Conference on Transdisciplinary Engineering, TE 2021 ; Conference date: 05-07-2021 Through 09-07-2021",
year = "2021",
month = oct,
day = "20",
doi = "10.3233/ATDE210077",
language = "English",
series = "Advances in Transdisciplinary Engineering",
publisher = "IOS Press BV",
pages = "13--22",
editor = "Linda Newnes and Susan Lattanzio and Moser, {Bryan R.} and Moser, {Bryan R.} and Stjepandic Josip and Nel Wognum",
booktitle = "Transdisciplinary Engineering for Resilience",
address = "Netherlands",
}
