TY - JOUR
T1 - Institutional, provider, and patient correlates of low-density lipoprotein and non-high-density lipoprotein cholesterol goal attainment according to the Adult Treatment Panel III guidelines
AU - Virani, Salim S.
AU - Woodard, Lechauncy D.
AU - Landrum, Cassie R.
AU - Pietz, Kenneth
AU - Wang, Degang
AU - Ballantyne, Christie M.
AU - Petersen, Laura A.
N1 - Funding Information:
Dr Virani has received honoraria from Abbott Laboratories and research grants from Merck and Co, Inc, and National Football League. Dr Ballantyne has received grant/research support from Abbott, AstraZeneca, GlaxoSmithKline, Merck, Sanofi-Synthelabo, Schering-Plough, and Takeda; is a consultant for Abbott, Amylin, Bristol-Myers Squibb, Kowa, Merck/Schering-Plough, Metabasis, NicOx, Novartis, Pfizer, Resverlogix, Roche, Sanofi-Synthelabo, Schering-Plough, and Takeda; is on the speakers' bureau for Merck/Schering-Plough, Pfizer, and Schering-Plough; and has received honoraria from Abbott, AstraZeneca, GlaxoSmithKline, Merck, Merck/Schering-Plough, Kowa, Novartis, Pfizer, Sanofi-Synthelabo, Schering-Plough, and Takeda. All other authors declare no relationships with industry.
Funding Information:
This work was supported by Investigator Initiated Research funding by Merck and Co, Inc , as well as the Houston VA Health Services Research & Development Center of Excellence (grant HFP90-020 ). Dr Virani is supported by a Department of Veterans Affairs Health Services Research and Development Service (HSR&D) Career Development Award ( CDA-09-028 ). This work was also supported in part by VA HSR&D PPO 09-316 (PI LeChauncy D. Woodard, MD, MPH), VA HSR&D IIR 04-349 (PI Laura A. Petersen, MD, MPH), and NIH R01 HL079173-0 1 (PI Laura A. Petersen, MD, MPH) and a VA contract ( Project XVA 33-120 ) at the request of Veterans Integrated Service Networks 1, 12, and 23. Dr Petersen was a Robert Wood Johnson Foundation Generalist Physician Faculty Scholar (045444) and an American Heart Association Established Investigator Awardee (0540043N) at the time this work was conducted.
PY - 2011/6
Y1 - 2011/6
N2 - Background: The aim of this analysis was to identify the proportion of coronary heart disease (CHD) patients achieving guideline-recommended low-density lipoprotein cholesterol (LDL-C) and non-high-density lipoprotein cholesterol (non-HDL-C) goals and to identify correlates of dual goal attainment. Methods: We analyzed patient, provider, and facility characteristics for 21,801 CHD patients in one Veterans Affairs Hospitals Network. Results: Low-density lipoprotein cholesterol goal attainment was 80%, but optional LDL-C goal attainment was 41%. Of patients with triglycerides ≥200 mg/dL, 51% attained both LDL-C and non-HDL-C goals. Correlates of higher dual goal attainment included older age (65-74 years: odds ratio [OR] 1.47, 95% CI 1.28-1.69), diabetes (OR 1.33, 95% CI 1.16-1.53), obesity (OR 1.25, 95% CI 1.04-1.50), a higher number of primary care visits (OR 1.04, 95% CI 1.04-1.05), and mild increase in illness severity of patients in provider's panel (OR 1.20, 95% CI 1.0008-1.46), whereas African American patients were less likely to achieve dual lipid goals (OR 0.63, 95% CI 0.48-0.82). Receipt of care from physician (vs nonphysician) or specialist (vs primary care) provider, number of patients in provider's panel, and percentage of patients in provider's panel with diagnosis of hyperlipidemia were not associated with dual goal attainment. Conclusions: A large proportion of CHD patients attained LDL-C goal, but optional LDL-C goal attainment was low. Patients with elevated triglycerides had poor attainment of dual LDL-C and non-HDL-C goals, suggesting a treatment gap. Factors associated with dual goal attainment may identify interventions needed to improve future guideline adherence.
AB - Background: The aim of this analysis was to identify the proportion of coronary heart disease (CHD) patients achieving guideline-recommended low-density lipoprotein cholesterol (LDL-C) and non-high-density lipoprotein cholesterol (non-HDL-C) goals and to identify correlates of dual goal attainment. Methods: We analyzed patient, provider, and facility characteristics for 21,801 CHD patients in one Veterans Affairs Hospitals Network. Results: Low-density lipoprotein cholesterol goal attainment was 80%, but optional LDL-C goal attainment was 41%. Of patients with triglycerides ≥200 mg/dL, 51% attained both LDL-C and non-HDL-C goals. Correlates of higher dual goal attainment included older age (65-74 years: odds ratio [OR] 1.47, 95% CI 1.28-1.69), diabetes (OR 1.33, 95% CI 1.16-1.53), obesity (OR 1.25, 95% CI 1.04-1.50), a higher number of primary care visits (OR 1.04, 95% CI 1.04-1.05), and mild increase in illness severity of patients in provider's panel (OR 1.20, 95% CI 1.0008-1.46), whereas African American patients were less likely to achieve dual lipid goals (OR 0.63, 95% CI 0.48-0.82). Receipt of care from physician (vs nonphysician) or specialist (vs primary care) provider, number of patients in provider's panel, and percentage of patients in provider's panel with diagnosis of hyperlipidemia were not associated with dual goal attainment. Conclusions: A large proportion of CHD patients attained LDL-C goal, but optional LDL-C goal attainment was low. Patients with elevated triglycerides had poor attainment of dual LDL-C and non-HDL-C goals, suggesting a treatment gap. Factors associated with dual goal attainment may identify interventions needed to improve future guideline adherence.
UR - https://www.scopus.com/pages/publications/79958083249
U2 - 10.1016/j.ahj.2011.03.023
DO - 10.1016/j.ahj.2011.03.023
M3 - Article
C2 - 21641361
AN - SCOPUS:79958083249
SN - 0002-8703
VL - 161
SP - 1140
EP - 1146
JO - American Heart Journal
JF - American Heart Journal
IS - 6
ER -