Intense fluorodeoxyglucose uptake in aggressive systemic mastocytosis without associated hematological neoplasm: Unusual fluorodeoxyglucose positron emission tomography/computed tomography presentation

Nosheen Fatima, Areeba Zaman, Sidra Zaman, Unaiza Zaman, Maseeh Zaman

Research output: Contribution to journalArticlepeer-review

Abstract

Systemic mastocytosis (SM) is a relatively rare heterogeneous group of disorders characterized by uncontrolled proliferation and accumulation of clonal mast cells in one or more organs. Indolent SM is the most common variety. Less common variety is aggressive systemic mastocytosis (aSM) type with or without associated hematological neopalsm (AHN). Fludeoxyglucose (FDG) positron emission tomography/computed tomography has a limited role in aSM without AHN as these exhibit low FDG avidity. We are presenting a biopsy-proven case of aSM without AHN showing abnormally high FDG uptake in lesions involving skin, nodes, marrow, and muscles.

Original languageEnglish
Pages (from-to)65-66
Number of pages2
JournalIndian Journal of Nuclear Medicine
Volume38
Issue number1
DOIs
Publication statusPublished - Jan 2023

Keywords

  • Aggressive systemic mastocytosis with associated hematological neopalsm
  • Aggressive systemic mastocytosis without associated hematological neopalsm
  • fludeoxyglucose positron emission tomography/computed tomography presentation
  • systemic mastocytosis

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