Intracranial metastasis of testicular germ cell tumours

Zara Shah, Hafiza Hifza Bashir, Saqib Kamran Bakhshi, Muhammad Shahzad Shamim

Research output: Contribution to journalArticlepeer-review


Brain metastasis from testicular germ cell tumour (TGCT) is rare and represents only 2% of metastatic brain tumours. Although TGCTs have a good survival rate, the prognosis of brain metastasis is poor. Due to the rarity of the diagnosis, there are limited studies on the topic and a standardized treatment protocol does not exist. Surgical management has long been considered a positive prognostic factor; however, recent studies have investigated the impact of chemotherapy and radiotherapy in these patients. Current literature suggests multiplicity of brain lesions and treatment with chemotherapy or radiotherapy alone can have a poor impact on the prognosis of the disease. However, studies with larger cohorts are required to understand and develop the optimal treatment protocol for patients with brain metastasis from TGCT.

Original languageEnglish
Pages (from-to)1137-1139
Number of pages3
JournalJournal of the Pakistan Medical Association
Issue number5
Publication statusPublished - May 2023


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