TY - JOUR
T1 - Intravenous dexamethasone along with caudal block improves analgesic efficacy following day-case inguinal hernia repair in children
T2 - A randomized controlled trial
AU - Nadeem, Amjad
AU - Ahmed, Aliya
PY - 2019/12/1
Y1 - 2019/12/1
N2 - OBJECTIVE: To assess the effectiveness of intravenous dexamethasone along with caudal block in improving analgesia following inguinal hernia repair in children. METHODS: The double-blind randomised controlled trial was conducted over a 6-month period from June 01, 2016 to November 30, 2016 at the Aga Khan University Hospital, Karachi, and comprised patients aged 1-5 years, scheduled for elective inguinal hernia repair. The subjects were randomised into two groups using the sealed envelope technique. Group D patients received 0.5mg/kg dexamethasone intravenous in 5ml, and group P was given placebo (5ml 0.9% saline). Assessment of postoperative pain was made through the faces, legs, activity, cry and consolability tool at 30 minutes and hourly for 4 hours. Rescue analgesia was given at pain score 3 or more with intravenous pethidine 0.5 mg/kg. SPSS 19 was used for data analysis. RESULTS: Of the 64 patients, there were 55(85.9%) boys and 9(14.1%) girls. The overall mean age was 29.8}13.8 months. The mean postoperative pain score was significantly higher in group P (p<0.05). At 30 minutes and two hours postoperatively, need for analgesia was also significantly higher in group P (p<0.05). CONCLUSIONS: In paediatric day-care inguinal hernia repair, dexamethasone could be used effectively for improving pain relief.
AB - OBJECTIVE: To assess the effectiveness of intravenous dexamethasone along with caudal block in improving analgesia following inguinal hernia repair in children. METHODS: The double-blind randomised controlled trial was conducted over a 6-month period from June 01, 2016 to November 30, 2016 at the Aga Khan University Hospital, Karachi, and comprised patients aged 1-5 years, scheduled for elective inguinal hernia repair. The subjects were randomised into two groups using the sealed envelope technique. Group D patients received 0.5mg/kg dexamethasone intravenous in 5ml, and group P was given placebo (5ml 0.9% saline). Assessment of postoperative pain was made through the faces, legs, activity, cry and consolability tool at 30 minutes and hourly for 4 hours. Rescue analgesia was given at pain score 3 or more with intravenous pethidine 0.5 mg/kg. SPSS 19 was used for data analysis. RESULTS: Of the 64 patients, there were 55(85.9%) boys and 9(14.1%) girls. The overall mean age was 29.8}13.8 months. The mean postoperative pain score was significantly higher in group P (p<0.05). At 30 minutes and two hours postoperatively, need for analgesia was also significantly higher in group P (p<0.05). CONCLUSIONS: In paediatric day-care inguinal hernia repair, dexamethasone could be used effectively for improving pain relief.
KW - Paediatric inguinal hernia, Dexamethasone, Anaesthesia, Analgesia
UR - http://www.scopus.com/inward/record.url?scp=85086496219&partnerID=8YFLogxK
U2 - 10.5455/JPMA.301035
DO - 10.5455/JPMA.301035
M3 - Article
C2 - 31853103
AN - SCOPUS:85086496219
SN - 0030-9982
VL - 69
SP - 1785
EP - 1789
JO - JPMA. The Journal of the Pakistan Medical Association
JF - JPMA. The Journal of the Pakistan Medical Association
IS - 12
ER -