Invasive Community Acquired Methicillin-Resistant Staphylococcal Aureus (CA-MRSA) Infections in Children

Muhammad Khalid, Samina Junejo, Fatima Mir

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

Staphylococci are gram-positive bacteria divided into coagulase positive and coagulase negative classes, Staphylococcus aureus is the most important bacterium of this class. Epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) has changed a lot. It is no more the problem of only hospitalised patients. Children coming from community has also been increasingly affected by MRSA-called community acquired methicillin-resistant (CA-MRSA) infection. The higher severity of CA-MRSA is due to its ability to produce the toxin Panton-Valentine Leukocidin (PVL) associated with staphylococcal cassette chromosome mec (SCCmec) type IV gene. Here, we are presenting five cases of CA-MRSA infection in children having age range 0.5 months to 11 years. All of them had invasive MRSA infection finally diagnosed as causing empyema thoracis, infective endocarditis, psoas abscess and necrotising fasciitis. Early surgical intervention, quick microbiological recognition of the pathogen, and appropriate antimicrobial therapy helped save their lives.

Original languageEnglish
Pages (from-to)S174-S177
JournalJournal of the College of Physicians and Surgeons--Pakistan : JCPSP
Volume28
Issue number9
DOIs
Publication statusPublished - 1 Sept 2018

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