TY - JOUR
T1 - Irritable bowel syndrome and psychiatric disorders in Pakistan
T2 - A case control study
AU - Butt, Amna Subhan
AU - Salih, Mohammad
AU - Jafri, Wasim
AU - Yakoob, Javed
AU - Wasay, Mohammad
AU - Hamid, Saeed
PY - 2012
Y1 - 2012
N2 - Background. The psychiatric disorders like anxiety and depression could have a profound influence on onset, expression, and course of Irritable bowel syndrome (IBS). Aim. To estimate the frequency and strength of association of common mental disorders (CMDs) in patients with IBS and patients with other chronic diseases, that is, migraine and hypertension. Method. This was a case control study. Individuals aged 18-70 years diagnosed as IBS were enrolled as cases. The control groups consisted of patients without IBS but diagnosed to have a chronic disease, that is, migraine or HTN. Self-Reporting Questonnaire-20(SRQ-20) was used as a screening tool for the detection of CMD. Results. 82 patients were enrolled in each group. Mean SRQ score was significantly higher in IBS group than controls (9.9 ± 4.5 versus 4.9 ± 3.6, P < 0.001). CMDs were more frequent (67.1 versus 22) and the odds of CMD were 7.24 times higher among IBS patients than controls (95 CI 3.6-14.5, P < 0.001). No difference was found in frequency of CMDs among various subtypes of IBS. Conclusion. We found that CMDs are more common and strongly associated with IBS as compared to other chronic diseases. Early screening for CMDs might be useful for an effective management of IBS.
AB - Background. The psychiatric disorders like anxiety and depression could have a profound influence on onset, expression, and course of Irritable bowel syndrome (IBS). Aim. To estimate the frequency and strength of association of common mental disorders (CMDs) in patients with IBS and patients with other chronic diseases, that is, migraine and hypertension. Method. This was a case control study. Individuals aged 18-70 years diagnosed as IBS were enrolled as cases. The control groups consisted of patients without IBS but diagnosed to have a chronic disease, that is, migraine or HTN. Self-Reporting Questonnaire-20(SRQ-20) was used as a screening tool for the detection of CMD. Results. 82 patients were enrolled in each group. Mean SRQ score was significantly higher in IBS group than controls (9.9 ± 4.5 versus 4.9 ± 3.6, P < 0.001). CMDs were more frequent (67.1 versus 22) and the odds of CMD were 7.24 times higher among IBS patients than controls (95 CI 3.6-14.5, P < 0.001). No difference was found in frequency of CMDs among various subtypes of IBS. Conclusion. We found that CMDs are more common and strongly associated with IBS as compared to other chronic diseases. Early screening for CMDs might be useful for an effective management of IBS.
UR - http://www.scopus.com/inward/record.url?scp=84858316958&partnerID=8YFLogxK
U2 - 10.1155/2012/291452
DO - 10.1155/2012/291452
M3 - Article
AN - SCOPUS:84858316958
SN - 1687-6121
JO - Gastroenterology Research and Practice
JF - Gastroenterology Research and Practice
M1 - 291452
ER -