ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update

Robin Lovell-Badge, Eric Anthony, Roger A. Barker, Tania Bubela, Ali H. Brivanlou, Melissa Carpenter, R. Alta Charo, Amander Clark, Ellen Clayton, Yali Cong, George Q. Daley, Jianping Fu, Misao Fujita, Andy Greenfield, Steve A. Goldman, Lori Hill, Insoo Hyun, Rosario Isasi, Jeffrey Kahn, Kazuto KatoJin Soo Kim, Jonathan Kimmelman, Jürgen A. Knoblich, Debra Mathews, Nuria Montserrat, Jack Mosher, Megan Munsie, Hiromitsu Nakauchi, Luigi Naldini, Gail Naughton, Kathy Niakan, Ubaka Ogbogu, Roger Pedersen, Nicolas Rivron, Heather Rooke, Janet Rossant, Jeff Round, Mitinori Saitou, Douglas Sipp, Julie Steffann, Jeremy Sugarman, Azim Surani, Jun Takahashi, Fuchou Tang, Leigh Turner, Patricia J. Zettler, Xiaomei Zhai

Research output: Contribution to journalReview articlepeer-review

139 Citations (Scopus)


The International Society for Stem Cell Research has updated its Guidelines for Stem Cell Research and Clinical Translation in order to address advances in stem cell science and other relevant fields, together with the associated ethical, social, and policy issues that have arisen since the last update in 2016. While growing to encompass the evolving science, clinical applications of stem cells, and the increasingly complex implications of stem cell research for society, the basic principles underlying the Guidelines remain unchanged, and they will continue to serve as the standard for the field and as a resource for scientists, regulators, funders, physicians, and members of the public, including patients. A summary of the key updates and issues is presented here.

Original languageEnglish
Pages (from-to)1398-1408
Number of pages11
JournalStem Cell Reports
Issue number6
Publication statusPublished - 8 Jun 2021
Externally publishedYes


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