Locally Aggressive Mixed Epithelial and Stromal Tumour of Kidney Leading to Nephron Loss

Mohammad Shoaib; Imran Khan Jalbani; Zeeshan Uddin; Ahsan Rafi; Farhat Abbas

doi:10.29271/jcpsp.2022.JCPSPCR.CR190

Locally Aggressive Mixed Epithelial and Stromal Tumour of Kidney Leading to Nephron Loss

Mohammad Shoaib, Imran Khan Jalbani, Zeeshan Uddin, Ahsan Rafi, Farhat Abbas

Research output: Contribution to journal › Article › peer-review

Abstract

Mixed epithelial and stromal tumour (MEST) is a rare benign renal tumour. It is mainly found in perimenopausal women. We present a case of a 42-year female with no known comorbid who was presented in the outpatient clinic for the right flank pain. Contrast-enhanced CT scan revealed a complex renal cyst with internal septations. Considering a large symptomatic cyst and the presence of internal septations, she was planned for cyst excision. Peroperatively, significant disease progression and loss of renal parenchyma were noted contrary to preoperative scan. Histopathology of the specimen revealed MEST. We demonstrate that MEST of the kidney may have an aggressive local behaviour leading to nephron loss.

Original language	English
Pages (from-to)	190-192
Number of pages	3
Journal	Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
Volume	32
DOIs	https://doi.org/10.29271/jcpsp.2022.JCPSPCR.CR190
Publication status	Published - Dec 2022

Keywords

Benign
Kidney
Mixed epithelial and stromal tumour
Renal neoplasm

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10.29271/jcpsp.2022.JCPSPCR.CR190

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title = "Locally Aggressive Mixed Epithelial and Stromal Tumour of Kidney Leading to Nephron Loss",

abstract = "Mixed epithelial and stromal tumour (MEST) is a rare benign renal tumour. It is mainly found in perimenopausal women. We present a case of a 42-year female with no known comorbid who was presented in the outpatient clinic for the right flank pain. Contrast-enhanced CT scan revealed a complex renal cyst with internal septations. Considering a large symptomatic cyst and the presence of internal septations, she was planned for cyst excision. Peroperatively, significant disease progression and loss of renal parenchyma were noted contrary to preoperative scan. Histopathology of the specimen revealed MEST. We demonstrate that MEST of the kidney may have an aggressive local behaviour leading to nephron loss.",

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T1 - Locally Aggressive Mixed Epithelial and Stromal Tumour of Kidney Leading to Nephron Loss

AU - Shoaib, Mohammad

AU - Jalbani, Imran Khan

AU - Uddin, Zeeshan

AU - Rafi, Ahsan

AU - Abbas, Farhat

PY - 2022/12

Y1 - 2022/12

N2 - Mixed epithelial and stromal tumour (MEST) is a rare benign renal tumour. It is mainly found in perimenopausal women. We present a case of a 42-year female with no known comorbid who was presented in the outpatient clinic for the right flank pain. Contrast-enhanced CT scan revealed a complex renal cyst with internal septations. Considering a large symptomatic cyst and the presence of internal septations, she was planned for cyst excision. Peroperatively, significant disease progression and loss of renal parenchyma were noted contrary to preoperative scan. Histopathology of the specimen revealed MEST. We demonstrate that MEST of the kidney may have an aggressive local behaviour leading to nephron loss.

AB - Mixed epithelial and stromal tumour (MEST) is a rare benign renal tumour. It is mainly found in perimenopausal women. We present a case of a 42-year female with no known comorbid who was presented in the outpatient clinic for the right flank pain. Contrast-enhanced CT scan revealed a complex renal cyst with internal septations. Considering a large symptomatic cyst and the presence of internal septations, she was planned for cyst excision. Peroperatively, significant disease progression and loss of renal parenchyma were noted contrary to preoperative scan. Histopathology of the specimen revealed MEST. We demonstrate that MEST of the kidney may have an aggressive local behaviour leading to nephron loss.

KW - Benign

KW - Kidney

KW - Mixed epithelial and stromal tumour

KW - Renal neoplasm

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SN - 1022-386X

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JO - Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

JF - Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

ER -

Locally Aggressive Mixed Epithelial and Stromal Tumour of Kidney Leading to Nephron Loss

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Keywords

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