TY - JOUR
T1 - Macro CK in patients with elevated troponin I levels
AU - Kohli-Kochhar, Ruchika
AU - Mulwa, Evelyne
AU - Omuse, Geoffrey
AU - Ojwang, Peter
PY - 2012/2/1
Y1 - 2012/2/1
N2 - CK-MB activity levels can be falsely elevated by the presence of macro CK, especially if immune-inhibition assays are used in the measurement. In patients with macro CK and cardiac pathology that could result in an elevated CK-MB activity, the diagnostic challenge lies in determining the true cause of the elevated CK-MB activity. We present two case reports of patients with elevated CK-MB activity and troponin I levels, but who subsequently had CK-MB activity higher than total CK activity, raising the suspicion of the presence of macro CK.
AB - CK-MB activity levels can be falsely elevated by the presence of macro CK, especially if immune-inhibition assays are used in the measurement. In patients with macro CK and cardiac pathology that could result in an elevated CK-MB activity, the diagnostic challenge lies in determining the true cause of the elevated CK-MB activity. We present two case reports of patients with elevated CK-MB activity and troponin I levels, but who subsequently had CK-MB activity higher than total CK activity, raising the suspicion of the presence of macro CK.
UR - http://www.scopus.com/inward/record.url?scp=84982278706&partnerID=8YFLogxK
U2 - 10.5830/CVJA-2010-082
DO - 10.5830/CVJA-2010-082
M3 - Article
C2 - 22331273
AN - SCOPUS:84982278706
SN - 1995-1892
VL - 23
SP - e7-e10
JO - Cardiovascular Journal of Africa
JF - Cardiovascular Journal of Africa
IS - 1
ER -