Malignancy in a vestibular schwannoma. Report of a case with central neurofibromatosis, treated by both stereotactic radiosurgery and surgical excision, with a review of the literature

M. E. Bari, D. M.C. Forster, A. A. Kemeny, L. Walton, D. Hardy, J. R. Anderson

Research output: Contribution to journalArticlepeer-review

76 Citations (Scopus)

Abstract

Malignant change in schwannoma is rare. Malignant change in a vestibular schwannoma (acoustic neuroma) is even more rare. This paper presents a case of rapidly growing vestibular schwannoma first treated by radiosurgery whose histopathology after surgical excision 42 months later showed malignant changes. Up to now, eight cases of malignancy in eighth nerve tumours have been reported, four of which, including the present case, had previously been treated with radiosurgery and four cases that had not received radiation. Thus, it would seem, the overall incidence is extremely low. Nevertheless, extreme vigilance and careful reporting continues to be necessary.

Original languageEnglish
Pages (from-to)284-289
Number of pages6
JournalBritish Journal of Neurosurgery
Volume16
Issue number3
DOIs
Publication statusPublished - 2002
Externally publishedYes

Keywords

  • Acoustic neuroma
  • Gamma knife
  • Radiosurgery
  • Vestibular schwannoma

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