Management of early rectal cancer: Current practice and future

Bhavani Mothe, Hasnain Zafar, Shakil Ahmed

Research output: Contribution to journalReview articlepeer-review

1 Citation (Scopus)


Early rectal cancer management includes tumour stages TiS, T1 and some selected T2 lesions that undergo appropriate clinical pre-operatie evaluation. Local excision of these lesions with acceptable recurrence rate can be achieved through various transanal endoscopic techniques like transanal endoscopic microsurgery (TEM) and transanal minimal invasive surgery (TAMIS) that are superior to simple transanal excision (TAE). The current literature review was planned to present the oncological evaluation of local excision in the context of available evidence. An overview of perioperative adjuvant therapies employed along with local excision is presented, with an update on the latest trials.

Original languageEnglish
Pages (from-to)1799-1806
Number of pages8
JournalJournal of the Pakistan Medical Association
Issue number10
Publication statusPublished - Oct 2020


  • Adjuvant therapy
  • Early rectal cancer
  • Rectal cancer
  • Salvage surgery
  • TEM
  • Transanal endoscopic microsurgery
  • Transanal minimally invasive surgery


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