TY - JOUR
T1 - Management of Sinonasal Tumors
T2 - Prognostic Factors and Outcomes: A 10 Year Experience at a Tertiary Care Hospital
AU - Kazi, Maliha
AU - Awan, Sohail
AU - Junaid, Montasir
AU - Qadeer, Sadaf
AU - Hassan, Nabeel Humayun
PY - 2013
Y1 - 2013
N2 - Sinonasal malignancies are said to be a highly heterogeneous group of cancers, accounting for less than 1 % of all cancers and less than 3 % of all upper aerodigestive tract tumors. Originating from any histologic components of the sinonasal cavity, the histopathology of these tumors is diverse. Accordingly, treatment options vary, surgery being the mainstay in most of them. Recurrence rates differs with each histological type of tumor, dependent on various factors. In this article, we have tried to identify the prevalent characteristics of sinonasal malignancies and to outline the prognostic factors affecting the outcome. It is a retrospective study design with a total number of 102 patients. Patients diagnosed with sinonasal malignancies were included and any patient previously operated outside our institute or having received prior radiation or chemotherapy were excluded. The patients were selected over a period of 10 years, from 2000 to 2010. Data was analyzed using SPSS 17. Majority of the sinonasal tumors were squamous cell carcinomas involving the maxillary sinus. Locoregional recurrence was found to be more frequent in patients with positive neck nodes on final histopathology. Sinonasal malignancies are mostly squamous cell in variety and recurrence of these rare entities is dependent on the histological variety and the presence of positive neck nodes.
AB - Sinonasal malignancies are said to be a highly heterogeneous group of cancers, accounting for less than 1 % of all cancers and less than 3 % of all upper aerodigestive tract tumors. Originating from any histologic components of the sinonasal cavity, the histopathology of these tumors is diverse. Accordingly, treatment options vary, surgery being the mainstay in most of them. Recurrence rates differs with each histological type of tumor, dependent on various factors. In this article, we have tried to identify the prevalent characteristics of sinonasal malignancies and to outline the prognostic factors affecting the outcome. It is a retrospective study design with a total number of 102 patients. Patients diagnosed with sinonasal malignancies were included and any patient previously operated outside our institute or having received prior radiation or chemotherapy were excluded. The patients were selected over a period of 10 years, from 2000 to 2010. Data was analyzed using SPSS 17. Majority of the sinonasal tumors were squamous cell carcinomas involving the maxillary sinus. Locoregional recurrence was found to be more frequent in patients with positive neck nodes on final histopathology. Sinonasal malignancies are mostly squamous cell in variety and recurrence of these rare entities is dependent on the histological variety and the presence of positive neck nodes.
KW - Locoregional recurrence
KW - Positive neck nodes
KW - Sinonasal malignancy
KW - Squamous cell carcinoma
UR - http://www.scopus.com/inward/record.url?scp=84880811552&partnerID=8YFLogxK
U2 - 10.1007/s12070-013-0650-x
DO - 10.1007/s12070-013-0650-x
M3 - Article
AN - SCOPUS:84880811552
SN - 2231-3796
VL - 65
SP - 155
EP - 159
JO - Indian Journal of Otolaryngology and Head and Neck Surgery
JF - Indian Journal of Otolaryngology and Head and Neck Surgery
IS - SUPPL 1
ER -