Maternal exposure to carbon monoxide and fine particulate matter during pregnancy in an urban Tanzanian cohort

B. J. Wylie, Y. Kishashu, E. Matechi, Z. Zhou, B. Coull, A. I. Abioye, K. L. Dionisio, F. Mugusi, Z. Premji, W. Fawzi, R. Hauser, M. Ezzati

Research output: Contribution to journalArticlepeer-review

41 Citations (Scopus)

Abstract

Low birthweight contributes to as many as 60% of all neonatal deaths; exposure during pregnancy to household air pollution has been implicated as a risk factor. Between 2011 and 2013, we measured personal exposures to carbon monoxide (CO) and fine particulate matter (PM2.5) in 239 pregnant women in Dar es Salaam, Tanzania. CO and PM2.5 exposures during pregnancy were moderately high (geometric means 2.0 ppm and 40.5 μg/m3); 87% of PM2.5 measurements exceeded WHO air quality guidelines. Median and high (75th centile) CO exposures were increased for those cooking with charcoal and kerosene versus kerosene alone in quantile regression. High PM2.5 exposures were increased with charcoal use. Outdoor cooking reduced median PM2.5 exposures. For PM2.5, we observed a 0.15 kg reduction in birthweight per interquartile increase in exposure (23.0 μg/m3) in multivariable linear regression; this finding was of borderline statistical significance (95% confidence interval 0.30, 0.00 kg; P = 0.05). PM2.5 was not significantly associated with birth length or head circumference nor were CO exposures associated with newborn anthropometrics. Our findings contribute to the evidence that exposure to household air pollution, and specifically fine particulate matter, may adversely affect birthweight.

Original languageEnglish
Pages (from-to)136-146
Number of pages11
JournalIndoor Air
Volume27
Issue number1
DOIs
Publication statusPublished - 1 Jan 2017
Externally publishedYes

Keywords

  • Birth outcome
  • Carbon monoxide
  • Household air pollution
  • Particulate matter
  • Personal exposure

Fingerprint

Dive into the research topics of 'Maternal exposure to carbon monoxide and fine particulate matter during pregnancy in an urban Tanzanian cohort'. Together they form a unique fingerprint.

Cite this