Mesenteric panniculitis associated with non-alcoholic fatty liver disease: A case series

Mehreen Siyal, Zaigham Abbas, Alina Saeed, Muhammad Ali Qadeer

Research output: Contribution to journalArticlepeer-review


Mesenter ic p anniculitis (MP) is a b enign infla mmatory condi tion of the abdomin al mesentery, whi ch presents with a wid e variety of symptoms. I t is diagnosed non - invasively through com puted to mography (CT ) scan, whereas biopsy is still co nside red th e gold standa rd. Steroids are the first line of treatment. Here, we report four cases who presented with abdominal pain. These patients were overweight and the CT scan findings were suggestive of mese nte ric panniculitis. Three cases had concomitant non- alcoholic steatohep atitis w ith el evated alanine transaminase levels, dyslipidaemia, and insulin resistance. FibroSca n showed moderate to severe steatosis. PNPLA3 rs738409 genotype was homozygous positive (GG) in one patient, whereas two patients were heterozygous positive (CG ). This a ssociat io n has not been well-described so far and w arrants f ur ther inve s tigation. There may be some common predisposing factors.

Original languageEnglish
Pages (from-to)993-997
Number of pages5
JournalJournal of the Pakistan Medical Association
Issue number5
Publication statusPublished - May 2024
Externally publishedYes


  • Dyslipidaemia
  • Insulin resistance
  • Mesenteric panniculitis
  • Non-alcoholic steatohepatitis


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