Microbiologic methods utilized in the MAL-ED cohort study

Eric Houpt; Jean Gratz; Margaret Kosek; Anita K.M. Zaidi; Shahida Qureshi; Gagandeep Kang; Sudhir Babji; Carl Mason; Ladaporn Bodhidatta; Amidou Samie; Pascal Bessong; Leah Barrett; Aldo Lima; Alexandre Havt; Rashidul Haque; Dinesh Mondal; Mami Taniuchi; Suzanne Stroup; Monica McGrath; Dennis Lang

doi:10.1093/cid/ciu413

Microbiologic methods utilized in the MAL-ED cohort study

Eric Houpt, Jean Gratz, Margaret Kosek, Anita K.M. Zaidi, Shahida Qureshi, Gagandeep Kang, Sudhir Babji, Carl Mason, Ladaporn Bodhidatta, Amidou Samie, Pascal Bessong, Leah Barrett, Aldo Lima, Alexandre Havt, Rashidul Haque, Dinesh Mondal, Mami Taniuchi, Suzanne Stroup, Monica McGrath, Dennis Lang

Division of Woman and Child Health, Medical College, Pakistan

Research output: Contribution to journal › Article › peer-review

85 Citations (Scopus)

Abstract

A central hypothesis of The Etiology, Risk Factors and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development (MAL-ED) study is that enteropathogens contribute to growth faltering. To examine this question, the MAL-ED network of investigators set out to achieve 3 goals: (1) develop harmonized protocols to test for a diverse range of enteropathogens, (2) provide quality-assured and comparable results from 8 global sites, and (3) achieve maximum laboratory throughput and minimum cost. This paper describes the rationale for the microbiologic assays chosen and methodologies used to accomplish the 3 goals.

Original language	English
Pages (from-to)	S225-S232
Journal	Clinical Infectious Diseases
Volume	59
DOIs	https://doi.org/10.1093/cid/ciu413
Publication status	Published - 1 Nov 2014

Keywords

ELISA
PCR
culture
enteropathogen
microscopy

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1093/cid/ciu413

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Houpt, E., Gratz, J., Kosek, M., Zaidi, A. K. M., Qureshi, S., Kang, G., Babji, S., Mason, C., Bodhidatta, L., Samie, A., Bessong, P., Barrett, L., Lima, A., Havt, A., Haque, R., Mondal, D., Taniuchi, M., Stroup, S., McGrath, M., & Lang, D. (2014). Microbiologic methods utilized in the MAL-ED cohort study. Clinical Infectious Diseases, 59, S225-S232. https://doi.org/10.1093/cid/ciu413

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abstract = "A central hypothesis of The Etiology, Risk Factors and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development (MAL-ED) study is that enteropathogens contribute to growth faltering. To examine this question, the MAL-ED network of investigators set out to achieve 3 goals: (1) develop harmonized protocols to test for a diverse range of enteropathogens, (2) provide quality-assured and comparable results from 8 global sites, and (3) achieve maximum laboratory throughput and minimum cost. This paper describes the rationale for the microbiologic assays chosen and methodologies used to accomplish the 3 goals.",

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Houpt, E, Gratz, J, Kosek, M, Zaidi, AKM, Qureshi, S, Kang, G, Babji, S, Mason, C, Bodhidatta, L, Samie, A, Bessong, P, Barrett, L, Lima, A, Havt, A, Haque, R, Mondal, D, Taniuchi, M, Stroup, S, McGrath, M & Lang, D 2014, 'Microbiologic methods utilized in the MAL-ED cohort study', Clinical Infectious Diseases, vol. 59, pp. S225-S232. https://doi.org/10.1093/cid/ciu413

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T1 - Microbiologic methods utilized in the MAL-ED cohort study

AU - Houpt, Eric

AU - Gratz, Jean

AU - Kosek, Margaret

AU - Zaidi, Anita K.M.

AU - Qureshi, Shahida

AU - Kang, Gagandeep

AU - Babji, Sudhir

AU - Mason, Carl

AU - Bodhidatta, Ladaporn

AU - Samie, Amidou

AU - Bessong, Pascal

AU - Barrett, Leah

AU - Lima, Aldo

AU - Havt, Alexandre

AU - Haque, Rashidul

AU - Mondal, Dinesh

AU - Taniuchi, Mami

AU - Stroup, Suzanne

AU - McGrath, Monica

AU - Lang, Dennis

PY - 2014/11/1

Y1 - 2014/11/1

N2 - A central hypothesis of The Etiology, Risk Factors and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development (MAL-ED) study is that enteropathogens contribute to growth faltering. To examine this question, the MAL-ED network of investigators set out to achieve 3 goals: (1) develop harmonized protocols to test for a diverse range of enteropathogens, (2) provide quality-assured and comparable results from 8 global sites, and (3) achieve maximum laboratory throughput and minimum cost. This paper describes the rationale for the microbiologic assays chosen and methodologies used to accomplish the 3 goals.

AB - A central hypothesis of The Etiology, Risk Factors and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development (MAL-ED) study is that enteropathogens contribute to growth faltering. To examine this question, the MAL-ED network of investigators set out to achieve 3 goals: (1) develop harmonized protocols to test for a diverse range of enteropathogens, (2) provide quality-assured and comparable results from 8 global sites, and (3) achieve maximum laboratory throughput and minimum cost. This paper describes the rationale for the microbiologic assays chosen and methodologies used to accomplish the 3 goals.

KW - ELISA

KW - PCR

KW - culture

KW - enteropathogen

KW - microscopy

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AN - SCOPUS:84906939349

SN - 1058-4838

VL - 59

SP - S225-S232

JO - Clinical Infectious Diseases

JF - Clinical Infectious Diseases

ER -

Microbiologic methods utilized in the MAL-ED cohort study

Abstract

Keywords

UN SDGs

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