Microbiologic methods utilized in the MAL-ED cohort study

Eric Houpt, Jean Gratz, Margaret Kosek, Anita K.M. Zaidi, Shahida Qureshi, Gagandeep Kang, Sudhir Babji, Carl Mason, Ladaporn Bodhidatta, Amidou Samie, Pascal Bessong, Leah Barrett, Aldo Lima, Alexandre Havt, Rashidul Haque, Dinesh Mondal, Mami Taniuchi, Suzanne Stroup, Monica McGrath, Dennis Lang

Research output: Contribution to journalArticlepeer-review

84 Citations (Scopus)


A central hypothesis of The Etiology, Risk Factors and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development (MAL-ED) study is that enteropathogens contribute to growth faltering. To examine this question, the MAL-ED network of investigators set out to achieve 3 goals: (1) develop harmonized protocols to test for a diverse range of enteropathogens, (2) provide quality-assured and comparable results from 8 global sites, and (3) achieve maximum laboratory throughput and minimum cost. This paper describes the rationale for the microbiologic assays chosen and methodologies used to accomplish the 3 goals.

Original languageEnglish
Pages (from-to)S225-S232
JournalClinical Infectious Diseases
Publication statusPublished - 1 Nov 2014


  • PCR
  • culture
  • enteropathogen
  • microscopy


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