Molecular imaging with 68Ga-PSMA PET/CT in high grade glioma: A biomarker for tumour neo-angiogenesis

Sharjeel Usmani; Khulood Al Riyami; Shah P. Numani; Syed Furqan Hashmi; Anjali Jain; Rashid al Sukaiti; Najeeb Ahmed; Muhammad Shahzad Shamim

doi:10.47391/JPMA.24-64

Molecular imaging with 68Ga-PSMA PET/CT in high grade glioma: A biomarker for tumour neo-angiogenesis

Sharjeel Usmani, Khulood Al Riyami, Shah P. Numani, Syed Furqan Hashmi, Anjali Jain, Rashid al Sukaiti, Najeeb Ahmed, Muhammad Shahzad Shamim

Department of Surgery, Medical College, Pakistan

Research output: Contribution to journal › Article › peer-review

Abstract

There are several promising radiotracers used for both staging and restaging of primary and recurrent brain tumours based on various mechanisms of tracer localization in tumour cells. 68Ga-PSMA PET has extremely low background uptake in normal brain tissue and consequently high tumour-to-brain ratio making it a promising imaging radiotracer for gliomas. 68Ga-PSMA demonstrates utility in evaluating high grade glioma during both initial workup or when suspecting recurrence. Herein the authors evaluate the role of this imaging modality and the potential future it holds in the management of high grade gliomas.

Original language	English
Pages (from-to)	1552-1554
Number of pages	3
Journal	Journal of the Pakistan Medical Association
Volume	74
Issue number	8
DOIs	https://doi.org/10.47391/JPMA.24-64
Publication status	Published - Aug 2024

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title = "Molecular imaging with 68Ga-PSMA PET/CT in high grade glioma: A biomarker for tumour neo-angiogenesis",

abstract = "There are several promising radiotracers used for both staging and restaging of primary and recurrent brain tumours based on various mechanisms of tracer localization in tumour cells. 68Ga-PSMA PET has extremely low background uptake in normal brain tissue and consequently high tumour-to-brain ratio making it a promising imaging radiotracer for gliomas. 68Ga-PSMA demonstrates utility in evaluating high grade glioma during both initial workup or when suspecting recurrence. Herein the authors evaluate the role of this imaging modality and the potential future it holds in the management of high grade gliomas.",

author = "Sharjeel Usmani and {Al Riyami}, Khulood and Numani, {Shah P.} and Hashmi, {Syed Furqan} and Anjali Jain and {al Sukaiti}, Rashid and Najeeb Ahmed and Shamim, {Muhammad Shahzad}",

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AU - Usmani, Sharjeel

AU - Al Riyami, Khulood

AU - Numani, Shah P.

AU - Hashmi, Syed Furqan

AU - Jain, Anjali

AU - al Sukaiti, Rashid

AU - Ahmed, Najeeb

AU - Shamim, Muhammad Shahzad

PY - 2024/8

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AB - There are several promising radiotracers used for both staging and restaging of primary and recurrent brain tumours based on various mechanisms of tracer localization in tumour cells. 68Ga-PSMA PET has extremely low background uptake in normal brain tissue and consequently high tumour-to-brain ratio making it a promising imaging radiotracer for gliomas. 68Ga-PSMA demonstrates utility in evaluating high grade glioma during both initial workup or when suspecting recurrence. Herein the authors evaluate the role of this imaging modality and the potential future it holds in the management of high grade gliomas.

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JO - Journal of the Pakistan Medical Association

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ER -

Molecular imaging with 68Ga-PSMA PET/CT in high grade glioma: A biomarker for tumour neo-angiogenesis

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