Multidrug-resistant gram-negative infections in transplant and oncology patients

Mehreen Arshad; Andrew Nowalk; Pranita D. Tamma

doi:10.1016/B978-0-323-64198-2.00023-3

Multidrug-resistant gram-negative infections in transplant and oncology patients

Mehreen Arshad, Andrew Nowalk, Pranita D. Tamma

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

2 Citations (Scopus)

Abstract

Multidrug-resistant gram-negative infections cause significant mortality and morbidity in the transplant and oncology patient population. Prolonged hospitalization and prior exposure to broad-spectrum antibiotics are common risk factors. Prevention strategies include daily bathing with chlorhexidine gluconate and use of isolation precautions. Recent data suggest that carbapenems provide adequate empiric therapy for most patients. However, culture data should be closely monitored to avoid overuse of broad-spectrum therapy.

Original language	English
Title of host publication	Pediatric Transplant and Oncology Infectious Diseases
Publisher	Elsevier
Pages	97-102.e3
ISBN (Electronic)	9780323641982
DOIs	https://doi.org/10.1016/B978-0-323-64198-2.00023-3
Publication status	Published - 1 Jan 2020
Externally published	Yes

Keywords

Epidemiology
Gram-negatives
Immunocompromised
Multidrug-resistance
Prevention
Treatment

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10.1016/B978-0-323-64198-2.00023-3

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abstract = "Multidrug-resistant gram-negative infections cause significant mortality and morbidity in the transplant and oncology patient population. Prolonged hospitalization and prior exposure to broad-spectrum antibiotics are common risk factors. Prevention strategies include daily bathing with chlorhexidine gluconate and use of isolation precautions. Recent data suggest that carbapenems provide adequate empiric therapy for most patients. However, culture data should be closely monitored to avoid overuse of broad-spectrum therapy.",

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AU - Nowalk, Andrew

AU - Tamma, Pranita D.

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AB - Multidrug-resistant gram-negative infections cause significant mortality and morbidity in the transplant and oncology patient population. Prolonged hospitalization and prior exposure to broad-spectrum antibiotics are common risk factors. Prevention strategies include daily bathing with chlorhexidine gluconate and use of isolation precautions. Recent data suggest that carbapenems provide adequate empiric therapy for most patients. However, culture data should be closely monitored to avoid overuse of broad-spectrum therapy.

KW - Epidemiology

KW - Gram-negatives

KW - Immunocompromised

KW - Multidrug-resistance

KW - Prevention

KW - Treatment

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DO - 10.1016/B978-0-323-64198-2.00023-3

M3 - Chapter

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SP - 97-102.e3

BT - Pediatric Transplant and Oncology Infectious Diseases

PB - Elsevier

ER -

Multidrug-resistant gram-negative infections in transplant and oncology patients

Abstract

Keywords

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