Multifocal oligodendroglioma with callosal and brainstem involvement

Fatima Mubarak, Kumail Khandwala, Shahzad M. Shamim, Madiha Bilal Qureshi

Research output: Contribution to journalArticlepeer-review


Background: Oligodendrogliomas are generally low-grade glial neoplasms commonly occurring in a cortical or subcortical location and frequently contain coarse calcifications. Tumors with 1p and 19q codeletions behave atypically and are more likely to have ill-defined margins and tend to have calcification. Very rarely, diffuse pattern and gliomatosis type of infiltrative nature of oligodendrogliomas have been described in sporadic case reports. Case Description: In this article, we present a case of a 31-year-old male who had diffuse multifocal oligodendroglioma with rare features of extensive callosal and brainstem involvement on imaging. Conclusion: Rare cases of oligodendrocytic gliomatosis cerebri or oligodendrogliomatosis with diffuse white matter spread of these tumors usually lead to a detrimental course of neurological status and a poor prognosis in these patients.

Original languageEnglish
Article number442
JournalSurgical Neurology International
Publication statusPublished - 2022


  • Brain
  • Infiltration
  • Oligodendroglioma
  • Spectroscopy
  • Tumor


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