Multiple sclerosis in Pakistan

Mohammad Wasay, S. Ali, I. A. Khati, A. Hassan, M. Asif, N. Zakiullah, A. Ahmed, A. Malik, B. Khealani, A. Haq, S. Fredrikson

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24 Citations (Scopus)


We describe retrospective data from the largest series of patients (n = 142) with multiple sclerosis (MS) from Pakistan. Mean age at onset was 27 years, with a female to male ratio of 1.45:1. The disease onset was polysymptomatic in 75% patients. Motor weakness was the most common onset symptom (70%), followed by sensory symptoms (45%). Optico-spinal type of MS was seen in only 3% of patients The courzse was relapsing-remitting (PP) 81%, primary progressive (PP) in 21%, and secondary progressive (SP) in 4% of patients. Almost three-fourths of the patients were moderately (45%) or severely (31%) disabled at the time of evaluation. Two-thirds of patients with severe disability had a mean disease duration of only 5.2 years. In conclusion, MS is not uncommon in Pakistan, and many patients were found to have severe disability despite short disease duration.

Original languageEnglish
Pages (from-to)668-669
Number of pages2
JournalMultiple Sclerosis Journal
Issue number5
Publication statusPublished - Jun 2007


  • Analysis
  • Multiple sclerosis
  • Pakistan
  • Review


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