National Cancer Registry of Pakistan: First Comprehensive Report of Cancer Statistics 2015-2019

Aamer Ikram, Shahid Pervez, Muhammad Tahir Khadim, Muhammad Sohaib, Hafeez Uddin, Farhana Badar, Ahmed Ijaz Masood, Zafar I.A. Khattak, Saima Naz, Tayyaba Rahat, Nighat Murad, Farah Naz Memon, Sumera Abid, Faiza Bashir, Ibrar Rafique, Muhammad Ayaz Mustafa, Roshan Kumar, Aisha Shafiq

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Objective: To compile a comprehensive national cancer registry report of Pakistan by merging and analysing cancer registration data received from major functional cancer registries in various parts of Pakistan. Study Design: Observational study. Place and Duration of the Study: Health Research Institute (HRI), National Institutes of Health (NIH), Islamabad, from 2015-2019. Methodology: Data from major cancer registries which included ‘Punjab Cancer Registry (PCR), ‘Karachi Cancer Registry (KCR)’, ‘Pakistan Atomic Energy Commission (PAEC) Cancer Registry’, Armed Forces Institute of Pathology (AFIP) Cancer Registry, Nishtar Medical University Hospital Multan (NMH), and Shifa International Hospital, Islamabad (SIH) registries were pooled, cleared, and analysed at HRI. Results: A total of 269,707 cancer cases were analysed. Gender-wise 46.7% were males and 53.61% were females. As per province-wise distribution, 45.13% of cases were from Punjab, 26.83% from Sindh, 16.46% from Khyber Pakhtunkhwa (KP), and 3.52% from Baluchistan. Both genders combined, ‘breast cancer’ 57633 (21.4%) was the most common cancer. In males, the top-5 cancers in order of frequency/percenatages were ‘oral’ 14477 (11.6%), ‘liver’ 8398 (6.73%), colorectal 8024 (6.43%), ‘lung’ 7547 (6.05%) and ‘prostate’ 7322 (5.87% cancers). In females, causes of the top-5-cancers included ‘breast’ 56250 (38.8%), ‘ovary’ 8823 (6.09%), ‘oral’ 7195 (4.97%), ‘cervix’ 6043 (4.17%), and ‘colorectal’ 4860 (3.36%) cancers. In children ‘Leukemia’ 1626 (14.50%) and in adolescents ‘Bone’ 880 (14%) were the leading malignancies. Conclusion: Breast cancer is the most common cancer in females touching epidemic proportions while ‘oral cancer’ which is the leading cancer in males ranks third in frequency in females. Like ‘oral cancer’ which shows a strong correlation with chewing, other common cancers in Pakistan including liver cancer, lung cancer, and cervical cancer are also largely preventable as showed a strong correlation with hepatitis B and C, smoking, and high-risk human papillomavirus.

Original languageEnglish
Pages (from-to)857-864
Number of pages8
JournalJournal of the College of Physicians and Surgeons--Pakistan : JCPSP
Issue number6
Publication statusPublished - 2023
Externally publishedYes


  • Health Research Institute - NIH
  • Islamabad
  • National Cancer Registry
  • Pakistan


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