TY - JOUR
T1 - Neonatal Infections in the Developing World
AU - Ganatra, Hammad A.
AU - Zaidi, Anita K.M.
PY - 2010/12
Y1 - 2010/12
N2 - An estimated one million newborns die from infections in developing countries. Despite the huge burden, high-quality data from community-based epidemiologic studies on etiology, risk factors, and appropriate management are lacking from areas in which newborns experience the greatest mortality. Several planned and ongoing studies in South Asia and Africa promise to address the knowledge gaps. However, simple and low-cost interventions, such as community-based neonatal care packages supporting clean birth practices, early detection of illness through use of clinical algorithms, and home-based antibiotic therapy in areas in which hospitalization is not feasible are already available and have the potential to bring about a drastic reduction in global neonatal mortality due to infections if they are scaled up to national level. Concerted collaborative action by national governments, health professionals, civil society organizations, and international health agencies is required to reduce neonatal mortality due to infections.
AB - An estimated one million newborns die from infections in developing countries. Despite the huge burden, high-quality data from community-based epidemiologic studies on etiology, risk factors, and appropriate management are lacking from areas in which newborns experience the greatest mortality. Several planned and ongoing studies in South Asia and Africa promise to address the knowledge gaps. However, simple and low-cost interventions, such as community-based neonatal care packages supporting clean birth practices, early detection of illness through use of clinical algorithms, and home-based antibiotic therapy in areas in which hospitalization is not feasible are already available and have the potential to bring about a drastic reduction in global neonatal mortality due to infections if they are scaled up to national level. Concerted collaborative action by national governments, health professionals, civil society organizations, and international health agencies is required to reduce neonatal mortality due to infections.
KW - Developing countries
KW - Infections
KW - Neonates
KW - Newborns
KW - Sepsis
UR - http://www.scopus.com/inward/record.url?scp=78549260040&partnerID=8YFLogxK
U2 - 10.1053/j.semperi.2010.09.004
DO - 10.1053/j.semperi.2010.09.004
M3 - Review article
C2 - 21094416
AN - SCOPUS:78549260040
SN - 0146-0005
VL - 34
SP - 416
EP - 425
JO - Seminars in Perinatology
JF - Seminars in Perinatology
IS - 6
ER -