Newborn weight nomograms in selected low and middle-income countries

Amy Sarah Ginsburg, Fyezah Jehan, Shabina Ariff, Muhammad Imran Nisar, Eric Schaefer, Valerie Flaherman, Akina Shrestha, Srijana Dongol, Victoria Laleau, Augusto Braima de Sa, Raimundo Co, Victoria Nankabirwa

Research output: Contribution to journalArticlepeer-review


Growth impairment is common in low- and middle-income countries (LMIC) and may begin during early infancy, increasing morbidity and mortality. To ensure healthy infant growth, healthcare providers in high-income countries (HIC) track newborn weight change using tools developed and validated in HIC. To understand the utility of these tools for LMIC, we conducted a secondary analysis to compare weight trajectories in the first 5 days of life among newborns born in our LMIC cohort to an existing HIC newborn weight tool designed to track early weight change. Between April 2019 and March 2020, a convenience sample of 741 singleton healthy breastfeeding newborns who weighed ≥ 2000 g at birth were enrolled at selected health facilities in Guinea-Bissau, Nepal, Pakistan, and Uganda. Using a standardized protocol, newborn weights were obtained within 6 h of birth and at 1, 2, 3, 4, and 5 days, and nomograms depicting newborn weight change were generated. The trajectories of early newborn weight change in our cohort were largely similar to published norms derived from HIC infants, with the exceptions that initial newborn weight loss in Guinea-Bissau was more pronounced than HIC norms and newborn weight gain following weight nadir was more pronounced in Guinea-Bissau, Pakistan, and Uganda than HIC norms. These data demonstrate that HIC newborn weight change tools may have utility in LMIC settings.

Original languageEnglish
Article number14128
JournalScientific Reports
Issue number1
Publication statusPublished - Dec 2023


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