Non-Hodgkin's thyroid lymphoma associated with Hashimoto's thyroiditis

Tamseela Ahmed, Muhammad Naeemul Haque, Naila Kayani, Zubair Ahmad

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10 Citations (Scopus)


We report two cases of thyroid lymphoma. First was of a 54-year-old lady who presented with a 10 year history of goiter. Examination revealed an enlarged thyroid gland extending sub-sternally, with no palpable lymph nodes. She had been on thyroxine for 4 months, due to a high TSH with positive antibodies. Fine needle aspiration cytology of thyroid showed Hashimoto thyroiditis (HT). A total thyroidectomy was done because of pressure symptoms. Histopathology revealed HT in right lobe and Diffuse Large B-cell Non-Hodgkin's lymphoma (DLBCL) in left lobe. Second case was of a 30 yearold man who presented with dyspnoea secondary to rapidly enlarging thyroid. On examination, thyroid was diffusely enlarged together with palpable lymph nodes. His TSH was elevated & Anti-TPO antibodies were positive suggesting an autoimmune etiology. Ultrasound showed an ill-defined heterogeneous mass in the left lobe of thyroid gland with multiple enlarged lymph nodes. Ultrasound guided thyroid core biopsy revealed DLBCL.

Original languageEnglish
Pages (from-to)342-344
Number of pages3
JournalJournal of the Pakistan Medical Association
Issue number3
Publication statusPublished - Mar 2014


  • Hashimoto thyroiditis
  • Non-Hodgkin's lymphoma
  • Thyroid lymphoma


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