TY - JOUR
T1 - Obsessive-compulsive disorder in the World Mental Health surveys
AU - The World Mental Health Survey collaborators
AU - Stein, Dan J.
AU - Ruscio, Ayelet Meron
AU - Altwaijri, Yasmin
AU - Chiu, Wai Tat
AU - Sampson, Nancy A.
AU - Aguilar-Gaxiola, Sergio
AU - Al-Hamzawi, Ali
AU - Alonso, Jordi
AU - Chardoul, Stephanie
AU - Gureje, Oye
AU - Hu, Chiyi
AU - Karam, Elie G.
AU - McGrath, John J.
AU - Navarro-Mateu, Fernando
AU - Scott, Kate M.
AU - Stagnaro, Juan Carlos
AU - Torres, Yolanda
AU - Vladescu, Cristian
AU - Wciórka, Jacek
AU - Xavier, Miguel
AU - Kessler, Ronald C.
AU - Zaslavsky, Alan M.
AU - Wojtyniak, Bogdan
AU - Williams, David R.
AU - Vigo, Daniel V.
AU - Viana, Maria Carmen
AU - Tintle, Nathan
AU - ten Have, Margreet
AU - Roest, Annelieke
AU - Posada-Villa, José
AU - Piazza, Marina
AU - Nishi, Daisuke
AU - Moskalewicz, Jacek
AU - Medina-Mora, Maria Elena
AU - Kovess-Masfety, Viviane
AU - Kiejna, Andrzej
AU - Kawakami, Norito
AU - Kazdin, Alan E.
AU - Karam, Georges
AU - Karam, Aimee Nasser
AU - de Jonge, Peter
AU - Hinkov, Hristo
AU - Harris, Meredith G.
AU - Haro, Josep Maria
AU - de Girolamo, Giovanni
AU - Degenhardt, Louisa
AU - Cardoso, Graça
AU - Caldas-de-Almeida, Jose Miguel
AU - Bunting, Brendan
AU - Atwoli, Lukoye
N1 - Publisher Copyright:
© The Author(s) 2025.
PY - 2025/12
Y1 - 2025/12
N2 - Background: National surveys have suggested that obsessive-compulsive disorder (OCD) is a prevalent and impairing condition. However, there are few cross-national data on OCD, with data particularly scarce in low- and middle-income countries. Here we employ data from the World Mental Health surveys to characterize the onset, course, severity, and treatment of OCD across a range of countries in different geographic regions of the world. Methods: Data came from general population surveys carried out in 10 countries (Argentina, Australia, Colombia, Iraq, Poland, People’s Republic of China, Portugal, Romania, Saudi Arabia, Spain) using a consistent research protocol and interview. A total of 26,136 adults were assessed for OCD in face-to-face interviews and were included in the present analyses. We examined lifetime and 12-month prevalence as well as age of onset, persistence, severity, and treatment of DSM-IV OCD in six high-income countries (HICs) and four low- or middle-income countries (LMICs). We also investigated socio-demographic variables and temporally prior mental disorders as predictors of OCD onset, persistence, severity, and treatment. Results: Across the 10 countries surveyed, OCD has a combined lifetime prevalence of 4.1%. The 12-month prevalence (3.0%) is nearly as high, suggesting a highly persistent course of illness. Age of onset is early, with more than 80% of OCD cases beginning by early adulthood. Most OCD cases in the community are mild (47.0%) or very mild (27.5%), with a smaller percentage designated as moderate (22.9%) or severe (2.7%) by the Yale-Brown Obsessive-Compulsive Scale. Only 19.8% of respondents with OCD received any mental health treatment in the past year, with treatment rates much higher in HICs (40.5%) than LMICs (7.0%). Cross-nationally, OCD commonly emerges in adolescence or early adulthood against a backdrop of earlier-occurring mental disorders. With few exceptions (e.g., prior social phobia), the socio-demographic and psychopathological risk factors for OCD onset, persistence, severity, and treatment are distinct. Conclusions: These cross-national data underscore clinical lessons regarding the importance of early diagnosis of OCD and comprehensive evaluation of comorbidity; draw attention to OCD as an undertreated disorder, particularly in LMIC contexts; and emphasize the public health significance of this often-overlooked condition.
AB - Background: National surveys have suggested that obsessive-compulsive disorder (OCD) is a prevalent and impairing condition. However, there are few cross-national data on OCD, with data particularly scarce in low- and middle-income countries. Here we employ data from the World Mental Health surveys to characterize the onset, course, severity, and treatment of OCD across a range of countries in different geographic regions of the world. Methods: Data came from general population surveys carried out in 10 countries (Argentina, Australia, Colombia, Iraq, Poland, People’s Republic of China, Portugal, Romania, Saudi Arabia, Spain) using a consistent research protocol and interview. A total of 26,136 adults were assessed for OCD in face-to-face interviews and were included in the present analyses. We examined lifetime and 12-month prevalence as well as age of onset, persistence, severity, and treatment of DSM-IV OCD in six high-income countries (HICs) and four low- or middle-income countries (LMICs). We also investigated socio-demographic variables and temporally prior mental disorders as predictors of OCD onset, persistence, severity, and treatment. Results: Across the 10 countries surveyed, OCD has a combined lifetime prevalence of 4.1%. The 12-month prevalence (3.0%) is nearly as high, suggesting a highly persistent course of illness. Age of onset is early, with more than 80% of OCD cases beginning by early adulthood. Most OCD cases in the community are mild (47.0%) or very mild (27.5%), with a smaller percentage designated as moderate (22.9%) or severe (2.7%) by the Yale-Brown Obsessive-Compulsive Scale. Only 19.8% of respondents with OCD received any mental health treatment in the past year, with treatment rates much higher in HICs (40.5%) than LMICs (7.0%). Cross-nationally, OCD commonly emerges in adolescence or early adulthood against a backdrop of earlier-occurring mental disorders. With few exceptions (e.g., prior social phobia), the socio-demographic and psychopathological risk factors for OCD onset, persistence, severity, and treatment are distinct. Conclusions: These cross-national data underscore clinical lessons regarding the importance of early diagnosis of OCD and comprehensive evaluation of comorbidity; draw attention to OCD as an undertreated disorder, particularly in LMIC contexts; and emphasize the public health significance of this often-overlooked condition.
KW - Community epidemiology
KW - Global mental health
KW - Obsessive-compulsive disorder
KW - World Mental Health surveys
UR - https://www.scopus.com/pages/publications/105010975159
U2 - 10.1186/s12916-025-04209-5
DO - 10.1186/s12916-025-04209-5
M3 - Article
C2 - 40629326
AN - SCOPUS:105010975159
SN - 1741-7015
VL - 23
JO - BMC Medicine
JF - BMC Medicine
IS - 1
M1 - 416
ER -