Ocular covid-19: Eyes as a reservoir to conceal and spread sars-cov-2

Abdul Mannan Baig, Saara Ahmad, Areeba Khaleeq, Hamna Rafique, Shafiqa Rajput, Mehaer Angez, Ayesha Hameed, Talha Nawaz, Preet Katyara

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

Ocular tissues can serve as a reservoir for the SARS-CoV-2 virus which can not only cause conjunctivitis but also serve as a source of infection transmission to others. Additionally, the eye and its tear drainage apparatus can track the SARS-CoV-2 from the eye into the respiratory tract of the patient. The potential ocular presence of the SARS-CoV-2 in the eye of a patient can target ACE2 receptors in the endothelium of the conjunctival vessels and use the lacrimal sac a potential space to evade immune detection and clinical isolation. The recently reported case of COVID-19 after the acquisition of SARS-CoV-2 from a COVID-19 patient should alert the health-care professionals dealing with COVID-19 patients that wearing masks alone cannot guarantee protection against infection transmission. Further studies, like isolation of SARS-CoV-2 from the eyes of patients with COVID-19, are needed to identify the eyes as a potential source of SARS-CoV-2 infection transmission.

Original languageEnglish (UK)
Pages (from-to)480-483
Number of pages4
JournalInfectious Disorders - Drug Targets
Volume21
Issue number4
DOIs
Publication statusPublished - 2021

Keywords

  • ACE2 receptors
  • Conjunctivitis
  • COVID-19
  • Ocular viral infections
  • Respiratory
  • SARS-CoV-2

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