Abstract
Ocular tissues can serve as a reservoir for the SARS-CoV-2 virus which can not only cause conjunctivitis but also serve as a source of infection transmission to others. Additionally, the eye and its tear drainage apparatus can track the SARS-CoV-2 from the eye into the respiratory tract of the patient. The potential ocular presence of the SARS-CoV-2 in the eye of a patient can target ACE2 receptors in the endothelium of the conjunctival vessels and use the lacrimal sac a potential space to evade immune detection and clinical isolation. The recently reported case of COVID-19 after the acquisition of SARS-CoV-2 from a COVID-19 patient should alert the health-care professionals dealing with COVID-19 patients that wearing masks alone cannot guarantee protection against infection transmission. Further studies, like isolation of SARS-CoV-2 from the eyes of patients with COVID-19, are needed to identify the eyes as a potential source of SARS-CoV-2 infection transmission.
| Original language | English (UK) |
|---|---|
| Pages (from-to) | 480-483 |
| Number of pages | 4 |
| Journal | Infectious Disorders - Drug Targets |
| Volume | 21 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 2021 |
Keywords
- ACE2 receptors
- Conjunctivitis
- COVID-19
- Ocular viral infections
- Respiratory
- SARS-CoV-2