Ongoing and future clinical trials of device therapies for patients with heart failure

Subaina Naeem Khalid, Taha Mansoor, Muhammad Ibraiz Bilal, Sardar Hassan Ijaz, Marat Fudim, Stephen J. Greene, Vijay Nambi, Salim S. Virani, Gregg C. Fonarow, Dmitry Abramov, Abdul Mannan Khan Minhas

Research output: Contribution to journalReview articlepeer-review

Abstract

Heart failure continues to pose a significant burden in terms of morbidity, mortality, and healthcare costs worldwide despite the implementation of guideline-directed medical therapy. Addressing this challenge and improving clinical outcomes for this patient population remains an urgent priority. Recognizing the limitations in current medical approaches and exploring strategies to overcome these limitations are crucial steps toward improving future outcomes. Various device-based interventions, such as Cardiac Resynchronization Therapy devices and Left Ventricular Assist Devices, have demonstrated notable benefits for individuals with heart failure. Our review is aimed at summarizing the ongoing research into new device therapies for heart failure, emphasizing their potential to overcome the current challenges in treatment. By utilizing Clinicaltrials.gov, an online repository, we conducted a comprehensive search for trials investigating emerging device therapies for patients dealing with heart failure.

Original languageEnglish
Article number102805
JournalCurrent Problems in Cardiology
Volume49
Issue number11
DOIs
Publication statusPublished - Nov 2024

Keywords

  • Cardiac failure
  • Clinical trials
  • Future

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