Optical map of the genotype A1 WB C6 Giardia lamblia genome isolate

D. Alexander Perry, Hilary G. Morrison, Rodney D. Adam

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)


The Giardia lamblia genome consists of 12 Mb divided among 5 chromosomes ranging in size from approximately 1 to 4 Mb. The assembled contigs of the genotype A1 isolate, WB, were previously mapped along the 5 chromosomes on the basis of hybridization of plasmid clones representing the contigs to chromosomes separated by PFGE. In the current report, we have generated an MluI optical map of the WB genome to improve the accuracy of the physical map. This has allowed us to correct several assembly errors and to better define the extent of the subtelomeric regions that are not included in the genome assembly.

Original languageEnglish
Pages (from-to)112-114
Number of pages3
JournalMolecular and Biochemical Parasitology
Issue number2
Publication statusPublished - Dec 2011
Externally publishedYes


  • Genome
  • Optical map
  • Pulsed field gel electrophoresis
  • Subtelomeric variation


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