Outcome of match related allogeneic stem cell transplantation procedures performed from 2004 till 2011

Natasha Ali; Salman Naseem Adil; Mohammad Usman Shaikh; Munira Moosajee; Nehal Masood

Outcome of match related allogeneic stem cell transplantation procedures performed from 2004 till 2011

Natasha Ali, Salman Naseem Adil, Mohammad Usman Shaikh, Munira Moosajee, Nehal Masood

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Abstract

We present our initial experience of allogeneic stem cell transplant procedure performed between April 2004 and August 2011 for various haematological disorders. All patients with non-malignant and malignant haematological disorders with HLA matched donors were selected after pre-transplant workup. Ninety seven patients underwent the procedure. Most common indications for transplant were aplastic anaemia in n=34 (35%), followed by beta-Thalassemia major in n=21 (21.6%) and chronic myeloid leukemia in n=11 patients (11.3%). Primary graft failure present was present in 2.06%. Incidence of graft versus host disease (GvHD) in our patients was 34%. After median follow-up of five years the overall survival was 71.3% with a mean survival time of 51.2±3.3months.

Original language	Undefined/Unknown
Journal	Department of Pathology and Laboratory Medicine
Publication status	Published - 1 Jan 2012

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Outcome of match related allogeneic stem cell transplantation pro

http://ecommons.aku.edu/pakistan_fhs_mc_pathol_microbiol/1085

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title = "Outcome of match related allogeneic stem cell transplantation procedures performed from 2004 till 2011",

abstract = "We present our initial experience of allogeneic stem cell transplant procedure performed between April 2004 and August 2011 for various haematological disorders. All patients with non-malignant and malignant haematological disorders with HLA matched donors were selected after pre-transplant workup. Ninety seven patients underwent the procedure. Most common indications for transplant were aplastic anaemia in n=34 (35%), followed by beta-Thalassemia major in n=21 (21.6%) and chronic myeloid leukemia in n=11 patients (11.3%). Primary graft failure present was present in 2.06%. Incidence of graft versus host disease (GvHD) in our patients was 34%. After median follow-up of five years the overall survival was 71.3% with a mean survival time of 51.2±3.3months.",

author = "Natasha Ali and Adil, {Salman Naseem} and Shaikh, {Mohammad Usman} and Munira Moosajee and Nehal Masood",

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AU - Ali, Natasha

AU - Adil, Salman Naseem

AU - Shaikh, Mohammad Usman

AU - Moosajee, Munira

AU - Masood, Nehal

PY - 2012/1/1

Y1 - 2012/1/1

N2 - We present our initial experience of allogeneic stem cell transplant procedure performed between April 2004 and August 2011 for various haematological disorders. All patients with non-malignant and malignant haematological disorders with HLA matched donors were selected after pre-transplant workup. Ninety seven patients underwent the procedure. Most common indications for transplant were aplastic anaemia in n=34 (35%), followed by beta-Thalassemia major in n=21 (21.6%) and chronic myeloid leukemia in n=11 patients (11.3%). Primary graft failure present was present in 2.06%. Incidence of graft versus host disease (GvHD) in our patients was 34%. After median follow-up of five years the overall survival was 71.3% with a mean survival time of 51.2±3.3months.

AB - We present our initial experience of allogeneic stem cell transplant procedure performed between April 2004 and August 2011 for various haematological disorders. All patients with non-malignant and malignant haematological disorders with HLA matched donors were selected after pre-transplant workup. Ninety seven patients underwent the procedure. Most common indications for transplant were aplastic anaemia in n=34 (35%), followed by beta-Thalassemia major in n=21 (21.6%) and chronic myeloid leukemia in n=11 patients (11.3%). Primary graft failure present was present in 2.06%. Incidence of graft versus host disease (GvHD) in our patients was 34%. After median follow-up of five years the overall survival was 71.3% with a mean survival time of 51.2±3.3months.

M3 - Article

JO - Department of Pathology and Laboratory Medicine

JF - Department of Pathology and Laboratory Medicine

ER -